Publications 2017

Liste des publications en 2017

- Smulski, C. R. ; Decossas, M. ; Chekkat, N. ; Beyrath, J. ; Willen, L. ; Guichard, G. ; Lorenzetti, R. ; Rizzi, M. ; Eibel, H. ; Schneider, P. ; Fournel, S., (2017) Hetero-Oligomerization between the Tnf Receptor Superfamily Members Cd40, Fas and Trailr2 Modulate Cd40 Signalling. Cell Death Dis, 8, (2), e2601.

- Nicolas-Boluda, A. ; Silva, A. K. A. ; Fournel, S. ; Gazeau, F., (2017) Physical Oncology : New Targets for Nanomedicine. Biomaterials, 150, 87-99.

- Spanedda, M. V. ; De Giorgi, M. ; Hassane, F. S. ; Schuber, F. ; Bourel-Bonnet, L. ; Frisch, B., (2017) Coupling of Ligands to the Liposome Surface by Click Chemistry. Methods Mol Biol, 1522, 93-106.

- Saliba, H. ; Heurtault, B. ; Bouharoun-Tayoun, H. ; Flacher, V. ; Frisch, B. ; Fournel, S. ; Chamat, S., (2017) Enhancing Tumor Specific Immune Responses by Transcutaneous Vaccination. Expert Rev Vaccines.
- Macho-Fernandez, E. ; Chekkat, N. ; Ehret, C. ; Thomann, J. S. ; De Giorgi, M. ; Spanedda, M. V. ; Bourel-Bonnet, L. ; Betbeder, D. ; Heurtault, B. ; Faveeuw, C. ; Fournel, S. ; Frisch, B. ; Trottein, F.,(2017) Solubilization of Alpha-Galactosylceramide in Aqueous Medium : Impact on Natural Killer T Cell Activation and Antitumor Responses. Int J Pharm , 530, (1-2), 354-363.

Publications 2016

Liste des publications en 2016

- Chiper, M., Tounsi, N., Kole, R., Kichler, A., Zuber, G. (2016) Self-aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides. Journal of Controlled Release, in press
- Ripoll, M., Neuberg, P., Kichler, A., Tounsi, N., Wagner, A., Remy, J.S. (2016) pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery. ACS Appl Mater Interfaces, in press.
- Moulay, G., Leborgne, C., Mason, A.J., Aisenbrey, C., Kichler, A., Bechinger, B. (2016) Histidine-rich designer peptides of the LAH4 family promote delivery of a multitude of cargo. Journal of Peptide Science, in press.
- Landa, M., Kotera, M., Remy, J.S., Badi, N. (2016) Preparation of poly(ethylene imine) derivatives with precisely controlled molecular weight. European Polymer Journal, in press.
- Beyrath, J. ; Chekkat, N. ; Smulski, C. R. ; Lombardo, C. M. ; Lechner, M. C. ; Seguin, C. ; Decossas, M. ; Spanedda, M. V. ; Frisch, B. ; Guichard, G. ; Fournel, S., (2016) Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels. Oncotarget, in press.
- Barallobre-Barreiro, J., Gupta, S.K., Zoccarato, A., Kitazume-Taneike, R., Fava, M., Yin, X., Werner, T., Hirt, M.N., Zampetaki, A., Viviano, A., Chong, M., Bern, M., Kourliouros, A., Domenech, N., Willeit, P., Shah, A.M., Jahangiri, M., Schaefer, L., Fischer, J.W., Iozzo, R.V., Viner, R., Thum, T., Heineke, J., Kichler, A., Otsu, K., Mayr, M. (2016) Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. Circulation. 134(11), 817-832.
- Wu, T., Heuillard, E., Linder, V., Bou About, G., Ignat, M., Dillenseger, J.P., Anton, N., Dalmier, E., Gosse, F., Foure, G., Blindauer, F., Giraudeau, C., El-Saghire, H., Bouhadjar, M., Calligaro, C., Sorg, T., Choquet, P., Vandamme, T.F., Ferrand, C., Marescaux, J., Baumert, T., Diana, M., Pessaux, P., Robinet, E. (2016) Multimodal Imaging of a Humanized Orthotopic Model of Hepatocellular Carcinoma in Immunodeficient Mice. Sci. Rep. 6, No. 35230.
- Bouchaala, R., Mercier, L., Andreiuk, B., Mély, Y., Vandamme, T.F., Anton, N., Goetz, J.G., Kymchenko, A.S. (2016) Integrity of lipid nanocarriers in bloodstream and tumor quantified by near-infrared ratiometric FRET imaging in living mice. J. Control. Release 236, 57-67.
- Akasov, R., Zaytseva-Zotova, R., Burov, S., Leko, M., Dontenwill, M., Chiper, M., Vandamme, T.F., Markvicheva, E. (2016) Formation of multicellular tumor spheroids induced by cyclic RGD-peptides and use for anticancer drug testing in vitro. Int. J. Pharm. 506, 148-57.
- Ding, S., Anton, N., Vandamme, T.F., Serra, C.A. (2016) Microfluidic nanoprecipitation systems for preparing pure drug or polymeric drug loaded nanoparticles : an overview. Exp. Op. Drug Deliv. 10, 1447-60.
- Attia, M.F., Anton, N., Khan, I.U., Serra, C.A., Messaddeq, N., Jakhmola, A., Vecchione, R., Vandamme, T.F. (2016) One-step synthesis of iron oxide polypyrrole nanoparticles encapsulating ketoprofen as model of hydrophobic drug. Int. J. Pharm. 508, 61-70.
- Attia, M.F., Anton, N., Akasov, R., Chiper, M., Markvicheva, E., Vandamme, T.F. (2016) Biodistribution and toxicity of X-ray iodinated contrast agent in nano-emulsions in function of their size. Pharm. Res. 33, 603-14.
- Akasov, R., Zaytseva-Zotova, D., Burov, S., Leko, M., Dontenwill, M., Chiper, M., Vandamme, T.F., Markvicheva, E. (2016) Formation of multicellular tumor spheroids induced by cyclic RGD-peptides and use for anticancer drug testing in vitro. Int. J. Pharm. 506, 148-57.
- Barthelemy, A. ; Ivanov, S. ; Hassane, M. ; Fontaine, J. ; Heurtault, B. ; Frisch, B. ; Faveeuw, C. ; Paget, C. ; Trottein, F., (2016) Exogenous Activation of Invariant Natural Killer T Cells by alpha-Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza. MBio , 7 (6).
- Bouche, M. ; Dahm, G. ; Wantz, M. ; Fournel, S. ; Achard, T. ; Bellemin-Laponnaz, S., (2016) Platinum(iv) N-heterocyclic carbene complexes : their synthesis, characterisation and cytotoxic activity. Dalton Trans, 45 (28), 11362-11368.
- Casset, A. ; Khayath, N. ; de Blay, F., (2016) How In Vitro Assays Contribute to Allergy Diagnosis. Curr Allergy Asthma Rep, 16 (11), 82.
- Chekkat, N. ; Dahm, G. ; Chardon, E. ; Wantz, M. ; Sitz, J. ; Decossas, M. ; Lambert, O. ; Frisch, B. ; Rubbiani, R. ; Gasser, G. ; Guichard, G. ; Fournel, S. ; Bellemin-Laponnaz, S., (2016) N-Heterocyclic Carbene-Polyethylenimine Platinum Complexes with Potent in Vitro and in Vivo Antitumor Efficacy. Bioconjug Chem, 27 (8), 1942-8.
- Diab, R. ; Virriat, A. S. ; Ronzani, C. ; Fontanay, S. ; Grandemange, S. ; Elaissari, A. ; Foliguet, B. ; Maincent, P. ; Leroy, P. ; Duvaj, R. E. ; Rihn, B. H. ; Joubert, O., (2016) Elaboration of Sterically Stabilized Liposomes for S-Nitrosoglutathione Targeting to Macrophages. J Biomed Nanotechnol, 12 (1), 217-30.
- Fend, L. ; Remy-Ziller, C. ; Foloppe, J. ; Kempf, J. ; Cochin, S. ; Barraud, L. ; Accart, N. ; Erbs, P. ; Fournel, S. ; Preville, X., (2016) Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment. Oncoimmunology, 5 (2), e1080414.
- Kakhi, Z. ; Frisch, B. ; Heurtault, B. ; Pons, F., (2016) Liposomal constructs for antitumoral vaccination by the nasal route. Biochimie, 130, 14-22.
- Pierrat, P., Kereselidze, D., Lux, M., Lebeau, L., Pons, F. (2016) Enhanced gene delivery to the lung using biodegradable polyunsaturated cationic phosphatidylcholine-detergent conjugates. Int. J. Pharm. 511, 205-218.
- Pierrat, P., Casset, A., Didier, P., Kereselidze, D., Lux, M., Pons, F., Lebeau, L. (2016) Cationic DOPC-Detergent Conjugates for Safe and Efficient in Vitro and in Vivo Nucleic Acid Delivery. Chembiochem. 17, 1771-83.
- Nothisen, M., Bagilet, J., Behr, J.P., Remy, J.S., Kotera, M. (2016) Structure Tuning of Cationic Oligospermine-siRNA Conjugates for Carrier-Free Gene Silencing. Mol. Pharm. 13, 2718-28.
- Muñoz, A., Sigwalt, D., Illescas, B. M., Luczkowiak, J., Rodriguez, L., Nierengarten, I., Holler, M., Remy, J.S., Buffet, K., Vincent, S. P., Rojo, J., Delgado, R., Nierengarten, J. F., and Martin, N. (2016) Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection. Nature Chem. 8, 50-57.
- Pierrat, P., Casset, A., Kereselidze, D., Lux, M., Pons, F., and Lebeau, L. (2016) DOPC-detergent conjugates : Fusogenic carriers for improved in vitro and in vivo gene delivery. Macromol. Biosci., 16(7), 984-989.
- El Shafey, N., Guesnon, M., Simon, F., Deprez, E., Cosette, J., Stockholm, D., Scherman, D., Bigey, P., and Kichler, A. (2016) Inhibition of the myostatin/Smad signaling pathway by short decorin-derived peptides. Exp. cell Res. 341, 187-95.
- Zuber, G. (2016) Amélioration du transfert cytosolique de protéines grâce à leur organisation dans un système de délivrance. Med. Sci. 32, 345-347.
- Majdoul, S., Seye, A.K., Kichler, A., Holic, N., Galy, A., Bechinger, B., and Fenard, D. (2016) Molecular determinants of vectofusin-1 and its derivatives for the enhancement of lentivirally mediated gene transfer into hematopoietic stem/progenitor cells. J. Biol. Chem. 291, 2161-2169.
- Simon-Yarza, M.T., Baati, T., Paci, A., Lesueur, L.L., Seck, A., Chiper, M., Gref, R., Serre, C., Couvreur, P., and Horcajada, P. (2016) Antineoplastic busulfan encapsulated in a metal organic framework nanocarrier : First in vivo results. J. Mater. Chem. B 4, 585-8.
- Attia, M.F., Anton, N., Akasov, R., Chiper, M., Markvicheva, E., and Vandamme, T.F. (2016) Biodistribution and toxicity of x-ray iodinated contrast agent in nano-emulsions in function of their size. Pharm. Res. 33, 603-14.
- Jacques, S., Leriche, G., Mosser, M., Nothisen, M., Muller, C., Remy, J.S., and Wagner, A. (2016) From solution to in-cell study of the chemical reactivity of acid sensitive functional groups : a rational approach towards improved cleavable linkers for biospecific endosomal release. Org. Biomol. Chem. 14, 4794-4803.
- Atto Al-Shuaeeb R., Kolodych, S., Koniev, O., Delacroix, S., Erb, S., Nicolay, S., Cintrat, J.C., Brion, J.D., Cianferani, S., Alami, M., Wagner, A., and Messaoudi S. (2016) Palladium-catalyzed chemoselective and biocompatible functionalization of cysteine-containing molecules at room temperature, Chem. Eur. J., 22(32), 11365-11370.
- Fend, L., Remy-Ziller, C., Foloppe, J., Kempf, J., Cochin, S., Barraud, L., Accart, N., Erbs, P., Fournel, S., and Preville, X. (2016) Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment. OncoImmunology 5, e1080414 1-11.
- Habermacher, C., Martz, A., Calimet, N., Lemoine, D., Peverini, L., Specht, A., Cecchini, M., and Grutter, T. (2016) Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel. eLife 5, e11050.
- Schmitt, J., Heitz, V., Sour, A., Bolze, F., Kessler, P., Flamigni, L., Ventura, B., Bonnet, C.S., and Toth, E. (2016) A theranostic agent combining a two-photon-absorbing photosensitizer for photodynamic therapy and a gadolinium(III) complex for MRI detection. Chem.-Eur. J. 22, 2775-86.
- Tam, D.Y., Dai, Z. ; Chan, M.S., Liu, L. S., Cheung, M.C., Bolze, F., Tin, C., and Lo, P.K., (2016) A reversible DNA logic gate platform operated by one- and two-photon excitations. Angew. Chem. Int. Ed. Engl. 55, 164-8.
- Piant, S., Specht, A., Zemelman, B., Losonczy, A., and Bolze, F. (2016) Two-photon sensitive photolabile protecting groups : From molecular engineering to nanostructuration. Mol. Cryst. Liquid Cryst. 627, 1-10.
- Piant, S., Bolze, F., and Specht, A., (2016) Two-photon uncaging, from neuroscience to materials. Opt. Mater. Express, 6(5), 1679−1691.
- Fichte, M. AH., Weyel, X. MM., Junek, S., Schäfer, F., Herbivo, C., Goeldner, M., Specht , A., Wachtveitl, J., Heckel, A., (2016) Three−Dimensional Control of DNA Hybridization by Orthogonal Two−Color Two−Photon Uncaging. Angew. Chem. Int. Ed. , 55(31), 8948−8952.
- Alam, M. M. ; Bolze, F. ; Daniel, C. ; Flamigni, L. ; Gourlaouen, C. ; Heitz, V. ; Jenni, S. ; Schmitt, J. ; Sour, A. ; Ventura, B., (2016) pi-Extended diketopyrrolopyrrole-porphyrin arrays : one- and two-photon photophysical investigations and theoretical studies. Phys Chem Chem Phys, 18 (31), 21954-65.
- Sour, A. ; Jenni, S. ; Orti-Suarez, A. ; Schmitt, J. ; Heitz, V. ; Bolze, F. ; Loureiro de Sousa, P. ; Po, C. ; Bonnet, C. S. ; Pallier, A. ; Toth, E. ; Ventura, B., (2016) Four Gadolinium(III) Complexes Appended to a Porphyrin : A Water-Soluble Molecular Theranostic Agent with Remarkable Relaxivity Suited for MRI Tracking of the Photosensitizer. Inorg Chem, 55 (9), 4545-54.
- Al-Shuaeeb, R. A. A. ; Kolodych, S. ; Koniev, O. ; Delacroix, S. ; Erb, S. ; Nicolaÿ, S. ; Cintrat, J.-C. ; Brion, J.-D. ; Cianférani, S. ; Alami, M. ; Wagner, A. ; Messaoudi, S., (2016) Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature. Chemistry – A European Journal, 22 (32), 11365-11370.
- Dovgan, I. ; Kolodych, S. ; Koniev, O. ; Wagner, A., (2016) 2-(Maleimidomethyl)-1,3-Dioxanes (MD) : a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation. Scientific Reports, 6, 30835.
- Liu, H. ; Audisio, D. ; Plougastel, L. ; Decuypere, E. ; Buisson, D.-A. ; Koniev, O. ; Kolodych, S. ; Wagner, A. ; Elhabiri, M. ; Krzyczmonik, A. ; Forsback, S. ; Solin, O. ; Gouverneur, V. ; Taran, F., (2016) Ultrafast Click Chemistry with Fluorosydnones. Angewandte Chemie International Edition, 55 (39), 12073-12077.
- Ursuegui, S. ; Mosser, M. ; Wagner, A., (2016) Copper-free click chemistry for microdroplet’s W/O interface engineering. RSC Advances, 6 (97), 94942-94948.

Publications 2015

Liste des publications en 2015

- Vranic, B.Z., and Vandamme, T.F. (2015) Preliminary study of an offline simultaneous determination of metoprolol tartrate and hydrochlorothiazide in powders and tablets by reflectance near-infrared spectroscopy. Pharm. Dev. Technol. 20, 99-104.
- Vranic, B.Z., and Vandamme, T.F. (2015) Effect of simulated precompression, compression pressure and tableting speed on an offline diffuse transmittance and reflectance near-infrared spectral information of model intact caffeine tablets. Pharm. Dev. Technol. 20, 90-98.
- Vandamme, T.F. (2015) Rodent models for human diseases. Eur. J. Pharmacol. 759, 84-89.
- Khan, I.U., Stolch, L., Serra, C. A., Anton, N., Akasov, R., and Vandamme, T.F. (2015) Microfluidic conceived pH sensitive core-shell particles for dual drug delivery. Int. J. Pharm. 478, 78-87.
- Khan, I.U., Serra, C.A., Anton, N., and Vandamme, T.F. (2015) Production of nanoparticle drug delivery systems with microfluidics tools. Expert Opin. Drug Deliv. 12, 547-562.
- Khan, I.U., Serra, C.A., Anton, N., Er-Rafik, M., Blanck, C., Schmutz, M., Kraus, I., Messaddeq, N., Sutter, C., Anton, H., Klymchenko, A.S., and Vandamme, T.F. (2015) Microfluidic conceived Trojan microcarriers for oral delivery of nanoparticles. Int. J. Pharm. 493, 7-15.
- Diouf, L.A., Mbaye, G., Ndiaye, A., Sy, P.M., Djiboune, A.R., Soumboundou, M., Ndiaye, I.E., Anton, N., Vandamme, T.F., and Diarra, M. (2015) Peanut oil based W1/O/W2 multiple emulsions for oral administration of insulin. Int. J. Curr. Res. 7, 22420-22423.
- Neuberg, P., Périno, A., Morin-Picardat, E., Anton, N., Darwich, Z., Weltin, D., Mely, Y., Klymchenko, A. S., Remy, J.S., and Wagner, A. (2015) Photopolymerized micelles of diacetylene amphiphile : physical characterization and cell delivery properties. Chem. Comm. 51, 11595-11598.
- Attia, M.F., Anton, N., Bouchaala, R., Didier, P., Arntz, Y., Messaddeq, N., Klymchenko, A.S., Mely, Y., and Vandamme, T.F. (2015) Functionalization of nano-emulsions with an amino-silica shell at the oil-water interface. RSC Adv. 5, 74353-74361.
- Martinčič, R., Kuzmanovski, I., Wagner, A., and Novic, M. (2015) Development of models for prediction of the antioxidant activity of derivatives of natural compounds. Anal. Chem. Acta. 868, 23–35.
- Kolodych, S., Koniev, O., Baatarkhuu, Z., Bonnefoy, J.Y., Debaene, F., Cianferani, S., Van Dorsselaer, A., Wagner, A. (2015) CBTF : New amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability. Bioconjugate Chem. 26,197-200.
- Jacques, S.A., Kuhn, I., Koniev, O., Schuber, F., Lund, F.E., Wagner, A., Muller-Steffner, H., and Kellenberger, E. (2015) Discovery of potent inhibitors of Schistosoma mansoni NAD+ catabolizing enzyme. J. Med. Chem. 8, 3582-92.
- Koniev, O., and Wagner, A. (2015) Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation. Chem. Soc. Rev. 44, 5495-5551.
- Neuberg, P., Périno, A., Morin-Picardat, E., Anton, N, Darwich, Z., Weltin, D. Mely, Y., Klymchenko, A.S., Remy, J.S., and Wagner, A. (2015) Photopolymerized micelles of diacetylene amphiphile : Physical characterization and cell delivery properties. Chem. Commun. 51, 11595-11598.
- Leriche, G., Jacques, S.A., Nothisen, M., Baumlin, N., Muller, C.D., Bagnard, D., Remy, J.S., Wagner, A. (2015) Spiro di-orthoester (SpiDo), a human plasma stable acid-sensitive cleavable linker for lysosomal release, Bioconjugate Chem. 26, 1461-1465.
- Koniev, O., Kolodych, S., Baatarkhuu, Z., Bonnefoy, J.Y., and Wagner, A. (2015) MAPN : New reagent for kinetically resolved thiol-to-thiol coupling. Bioconjugate Chem. 26, 1863−1867.
- Flacher, V., Neuberg, P., Point, F., Daubeuf, F., Muller, Q., Sigwalt, D., Fauny, J.D., Remy, J.S., Frossard, N., Wagner, A., Mueller, C.G., and Schaeffer, E.(2015) Mannoside glycolipid conjugates display antiinflammatory activity by inhibition of Toll-like Receptor-4 mediated cell activation. ACS Chem. Biol. 10, 2697-2705.
- Spanedda, M.V., Salome, C., Hilbold, B., Berner, E., Heurtault, B., Fournel, S., Frisch, B., and Bourel-Bonnet, L. (2015) Smart tools and orthogonal click-like reactions onto small unilamellar vesicles : Additional molecular data. Data in Brief 5, 145-154.
- Salome, C., Spanedda, M.V., Hilbold, B., Berner, E., Heurtault, B., Fournel, S., Frisch, B., and Bourel-Bonnet, L. (2015) Smart tools and orthogonal click-like reactions onto small unilamellar vesicles. Chem. Phys. Lipids 188, 27-36.
- Rios, C., Longo, J., Zahouani, S., Garnier, T., Vogt, C., Reisch, A., Senger, B., Boulmedais, F., Hemmerle, J., Benmlih, K., Frisch, B., Schaaf, P., Jierry, L., and Lavalle, P. (2015) A new biomimetic route to engineer enzymatically active mechano-responsive materials. Chem. Commun. 51, 5622-5.
- Kakhi, Z., Frisch, B., Bourel-Bonnet, L., Hemmerle, J., Pons, F., and Heurtault, B. (2015) Airway administration of a highly versatile peptide-based liposomal construct for local and distant antitumoral vaccination. Int. J. Pharm. 496, 1047-56.
- Pulka-Ziach, K., Pavet, V., Chekkat, N., Estieu-Gionnet, K., Rohac, R., Lechner, M. C., Smulski, C. R., Zeder-Lutz, G., Altschuh, D., Gronemeyer, H., Fournel, S., Odaert, B., and Guichard, G. (2015) Thioether analogues of disulfide-bridged cyclic peptides targeting death receptor 5 : conformational analysis, dimerisation and consequences for receptor activation. Chembiochem 16, 293-301.
- Pierrat, P., Wang, R., Kereselidze, D., Lux, M., Didier, P., Kichler, A., Pons, F., and Lebeau, L. (2015) Efficient in vitro and in vivo pulmonary delivery of nucleic acid by carbon dot-based nanocarriers. Biomaterials 51, 290-302.
- Kellenberger, S., and Grutter, T. (2015) Architectural and Functional Similarities between Trimeric ATP gated P2X receptors and acid-sensing ion channels. J. Mol. Biol. 427, 54-66.
- Habermacher, C., Dunning, K., Chataigneau, T., and Grutter, T. (2015) Molecular structure and function of P2X receptors. Neuropharmacol. 104, 18-30.
- Schmitt, J., Heitz, V., Sour, A., Bolze, F., Ftouni, H., Nicoud, J.F., Flamigni, L., and Ventura, B. (2015) Diketopyrrolopyrrole-porphyrin conjugates with high two-photon absorption and singlet oxygen generation for two-photon photodynamic therapy. Angew. Chem. Int. Ed. Engl. 54, 169-173.
- Guo, L., Chan, M.S., Xu, D., Tam, D.Y., Bolze, F., Lo, P.K., and Wong, M. S. (2015) Indole-based cyanine as a nuclear RNA-selective two-photon fluorescent probe for live cell imaging. ACS Chem. Biol. 10, 1171-1175.
- Dai, Z., Tam, D.Y., Xu, H., Chan, M.S., Liu, L.S., Bolze, F., Sun, X.H., and Lo, P.K. (2015) Conformational change of self-assembled DNA nanotubes induced by two-photon excitation. Small 11, 4090-4096.
- Chang, Y., Michelin, C., Bucher, L., Desbois, N., Gros, C.P., Piant, S., Bolze, F., Fang, Y., Jiang, X., and Kadish, K.M. (2015) Synthesis and characterization of carbazole-linked porphyrin tweezers. Chem.-Eur. J. 21, 12018-12025.
- Niehl, A. ; Appaix, F. ; Bosca, S., van der Sanden, B. ; Nicoud, J.F. ; Bolze, F., and Heinlein, M. (2015) Fluorescent tobacco mosaic virus-derived bio-nanoparticles for intravital two-photon imaging. Front. Plant Sci. 6, 1244.
- Douat, C., Aisenbrey, C., Antunes, S., Decossas, M., Lambert, O., Bechinger, B., Kichler, A., and Guichard, G. (2015) A cell-penetrating foldamer with a bioreducible linkage for intracellular delivery of DNA. Angew. Chem. Int. Ed. Engl. 54, 11133-7.
- Flacher, V., Neuberg, P., Point, F., Daubeuf, F., Muller, Q., Sigwalt, D., Fauny, J.D., Remy, J.S., Frossard, N., Wagner, A., Mueller, C.G., and Schaeffer, E. (2015) Mannoside glycolipid conjugates display antiinflammatory activity by inhibition of Toll-like Receptor-4 mediated cell activation. ACS Chem. Biol. 10, 2697-705.
- Orlov, I., Schertel, A., Zuber, G., Klaholz, B., Drillien, R., Weiss, E., Schultz, P., and Spehner, D. (2015) Live cell immunogold labelling of RNA polymerase II. Sci. Rep. 5, 8324.
- Ouahabi, A.A., Kotera, M., Charles, L., and Lutz, J.F. (2015) Synthesis of monodisperse sequence-coded polymers with chain lengths above DP100. ACS Macro Lett. 4, 1077-1080.
- Pierrat, P., and Lebeau, L. (2015) Characterization of titratable mmphiphiles in lipid membranes by fluorescence spectroscopy. Langmuir 31, 12362-12371.
- Pierrat, P., Wang, R., Kereselidze, D., Lux, M., Didier, P., Kichler, A., Pons, F., and Lebeau, L. (2015) Efficient in vitro and in vivo pulmonary delivery of nucleic acid by carbon dot-based nanocarriers. Biomaterials 51, 290-302.
- Postupalenko, V., Desplancq, D., Orlov, I., Arntz, Y., Spehner, D., Mely, Y., Klaholz, B. P., Schultz, P., Weiss, E., and Zuber, G. (2015) Protein delivery system containing a nickel-immobilized polymer for multimerization of affinity-purified His-tagged proteins enhances cytosolic transfer. Angew. Chem. Int. Ed. Engl. 54, 10583-10586.
- Yan, W., Seifermann, S. M., Pierrat, P., and Braese, S. (2015) Synthesis of highly functionalized C-60 fullerene derivatives and their applications in material and life sciences. Org. Biomol.Chem. 13, 25-54.
- Neuberg, P., Périno, A., Morin-Picardat, E., Anton, N, Darwich, Z., Weltin, D. Mely, Y., Klymchenko, A.S., Remy, J.S., Wagner, A. (2015) Photopolymerized micelles of diacetylene amphiphile : Physical characterization and cell delivery properties. Chem. Commun. 51, 11595-11598.
- Leriche, G., Jacques, S.A., Nothisen, M., Baumlin, N., Muller, C.D., Bagnard, D., Remy, J.S., Wagner, A. (2015) Spiro di-orthoester (SpiDo), a human plasma stable acid-sensitive cleavable linker for lysosomal release, Bioconjugate Chem. 26, 1461-1465.

Publications 2014

Liste des publication en 2014

- Kuhn, I., Kellenberger, E., Cakir-Kiefer, C., Muller-Steffner, H., and Schuber, F. (2014) Probing the catalytic mechanism of bovine CD38/NAD(+)glycohydrolase by site directed mutagenesis of key active site residues. Biochim. Biophys. Acta 1844, 1317-1331.
- Bevilacqua, V., King, M., Chaumontet, M., Nothisen, M., Gabillet, S., Buisson, D., Puente, C., Wagner, A., and Taran, F. (2014) Copper-chelating azides for efficient click conjugation reactions in complex media. Angew. Chem. 126, 5982-5986.
- King, M., and Wagner, A. (2014) Developments in the field of bioorthogonal bond forming reactions—Past and present trends. Bioconjugate Chem. 25, 825–839.
- Egloff, C., Weltin, D., Calligaro, C., Mosser, M., Nothisen, M., Remy, J.S., and Wagner, A. (2014) Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe : Application to living-cell biothiol imaging. Chem. Commun. 50, 10049-10051.
- Plougastel, L., Koniev, O., Specklin, S., Decuypere, E., Créminon, C., Buisson, D., Wagner, A., Kolodych, S., and Taran, F. (2014) 4-Halogeno-sydnones for fast strain promoted cycloaddition with cyclooctynes. Chem. Commun. 50, 9376-9378.
- Ronzani, C., Casset, A., and Pons, F. (2014) Exposure to multi-walled carbon nanotubes results in aggravation of airway inflammation and remodeling and in increased production of epithelium-derived innate cytokines in a mouse model of asthma. Arc.h Toxicol. 88, 489-99.
- Reisch, A., Roger, E., Phoeung, T., Antheaume, C., Orthlieb, C., Boulmedais, F., Lavalle, P., Schlenoff, J. B., Frisch, B., and Schaaf, P. (2014) On the benefits of rubbing salt in the cut : Self-healing of saloplastic paa/pah compact polyelectrolyte complexes. Adv. Mater. 26, 2547-51.
- Macho-Fernandez, E., Cruz, L. J., Ghinnagow, R., Fontaine, J., Bialecki, E., Frisch, B., Trottein, F., and Faveeuw, C. (2014) Targeted delivery of alpha-galactosylceramide to CD8alpha+ dendritic cells optimizes type I NKT cell-based antitumor responses. J. Immunol. 193, 961-9.
- Heurtault, B., Reix, N., Meyer, N., Gasser, F., Wendling, M. J., Ratomponirina, C., Jeandidier, N., Sapin, R., and Agin, A. (2014) Extensive study of human insulin immunoassays : promises and pitfalls for insulin analogue detection and quantification. Clin. Chem. Lab. Med. 52, 355-62.
- Fend, L., Gatard-Scheikl, T., Kintz, J., Gantzer, M., Schaedler, E., Rittner, K., Cochin, S., Fournel, S., and Preville, X. (2014) Intravenous injection of MVA virus targets CD8+ lymphocytes to tumors to control tumor growth upon combinatorial treatment with a TLR9 agonist. Cancer Immunol. Res. 2, 1163-1174.
- Casset, A., Meunier-Spitz, M., Rebotier, P., Lefevre, H., Barth, C., Heitz, C., and de Blay, F. (2014) Asthma management and inhalation techniques among community pharmacists in 2009 : a comparison with the 1999 survey. J. Asthma 51, 964-73.
- Pinel, S., Aman, E., Erblang, F., Dietrich, J., Frisch, B., Sirman, J., Kichler, A., Sibler, A. P., Dontenwill, M., Schaffner, F., and Zuber, G. (2014) Quantitative measurement of delivery and gene silencing activities of siRNA polyplexes containing pyridylthiourea-grafted polyethylenimines. J. control. Release 182C, 1-12.
- Attia, M. F., Anton, N., Chiper, M., Akasov, R., Anton, H., Messaddeq, N., Fournel, S., Klymchenko, A. S., Mely, Y., and Vandamme, T. F. (2014) Biodistribution of x-ray iodinated contrast agent in nano-emulsions is controlled by the chemical nature of the oily core. ACS nano 8, 10537-50.
- Garcia-Fernandez, L., Specht, A., and del Campo, A. (2014) A polyurethane-based positive photoresist. Macromol. Rapid Commun. 35, 1801-1807.
- Garcia-Fernandez, L., Herbivo, C., Arranz, V.S.M., Warther, D., Donato, L., Specht, A., and del Campo, A. (2014) Dual photosensitive polymers with wavelength-selective photoresponse. Adv. Mater. 26, 5012-5017.
- Bevilacqua, V., King, M., Chaumontet, M., Nothisen, M., Gabillet, S., Buisson, D., Puente, C., Wagner, A., and Taran, F. (2014) Copper-chelating azides for efficient click conjugation reactions in complex media. Angew. Chem. Int. Ed. Engl. 53, 5872-5876.
- Egloff, C., Jacques, S.A., Nothisen, M., Weltin, D., Calligaro, C., Mosser, M., Remy, J.S., and Wagner, A. (2014) Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe : application to living-cell biothiol imaging. Chem. Commun. 50, 10049-10051.
- Koniev, O., Leriche, G., Nothisen, M., Remy, J.S., Strub, J.M., Schaeffer-Reiss, C., Van Dorsselaer, A., Baati, R., and Wagner, A. (2014) Selective irreversible chemical tagging of cysteine with 3-arylpropiolonitriles. Bioconjugate Chem. 25, 202-206.
- Mahindhoratep, S., Bouda, H.A., El Shafey, N., Scherman, D., Kichler, A., Pichon, C., Midoux, P., Mignet, N., and Bureau, M.F. (2014) NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer. Biochim. Biophys. Acta 1840, 3257-63.
- Pinel, S., Aman, E., Erblang, F., Dietrich, J., Frisch, B., Sirman, J., Kichler, A., Sibler, A.P., Dontenwill, M., Schaffner, F., and Zuber, G. (2014) Quantitative measurement of delivery and gene silencing activities of siRNA polyplexes containing pyridylthiourea-grafted polyethylenimines. J. Control. Release 182, 1-12.
- Li, X., Anton, N., Zuber, G., and Vandamme, T.F. (2014) Contrast agents for preclinical targeted X-ray imaging. Adv. Drug Deliv. Rev. 76, 116-133.
- Postupalenko, V., Sibler, A.P., Desplancq, D., Nominé, Y., Spehner, D., Schultz, P., Weiss, E., and Zuber, G. (2014) Intracellular delivery of functionally active proteins using self-assembling pyridylthioureapolyethylenimine. J. Control. Release 178, 86-94.
- Vandamme, T.F., Anton, N., and Torchilin, V. (2014) Targeted imaging Preface. Adv. Drug Deliv. Rev. 76, 1-1.
- Vandamme, T.F. (2014) New oral anthelmintic intraruminal delivery device for cattle. J. Pharm. Bioallied Sci. 6, 31-37.
- Vandamme, T.F. (2014) Use of rodents as models of human diseases. J. Pharm. Bioallied Sci. 6, 2-9.
- Khan, I.U., Serra, C.A., Anton, N., Vandamme, T.F. (2014) Production of nanoparticle drug delivery systems with microfluidic tools. Expert Opin. Drug Deliv. 1-16.
- Kilin, V., Anton, H., Anton, N., Steed, E., Vermot, J., Vandamme, T.F., Mely, Y., and Klymchenko, A.S. (2014) Counterion-enhanced cyanine dye loading into lipid nano-droplets for single particle tracking in zebrafish. Biomaterials 35, 4950-4957.
- Supper, S., Anton, N., Seidel, N., Riemenschnitter, M., Curdy, C., and Vandamme, T.F. (2014) Thermosensitive chitosan/glycerophosphate-based hydrogel and its derivatives in pharmaceutical and biomedical applications. Expert Opin. Drug Deliv. 11, 249-267.
- Supper, S., Anton, N., Boisclair, J., Seidel, N., Riemenschnitter, M., Curdy, C., and Vandamme, T.F. (2014) Chitosan/glucose 1-phosphate as new stable in situ forming depot system for controlled drug delivery. Eur. J. Pharm. Biopharm. 88, 361-373. (18) Phuc Nghia, N., Veschgini, M., Tanaka, M., Waton, G., Vandamme, T.F., and , M.P. (2014), Counteracting the inhibitory effect of proteins towards lung surfactant substitutes : a fluorocarbon gas helps displace albumin at the air/water interface. Chem. Commun. 50, 11576-11579.
- Li, X., Anton, N., Zuber, G., and Vandamme, T.F. (2014) Contrast agents for preclinical targeted X-ray imaging. Adv. Drug Deliv. Rev. 76, 116-133.
- Khan, I.U., Serra, C. A., Anton, N., Li, X., Akasov, R., Messaddeq, N., Kraus, I., and Vandamme, T.F. (2014) Microfluidic conceived drug loaded Janus particles in side-by-side capillaries device. Int. J. Pharm. 473, 239-249.
- Jakhmola, A., Anton, N., Anton, H., Messaddeq, N., Hallouard, F., Klymchenko, A., Mely, Y., and Vandamme, T.F. (2014) Poly-epsilon-caprolactone tungsten oxide nanoparticles as a contrast agent for X-ray computed tomography. Biomaterials 35, 2981-2986.
- Attia, M.F., Anton, N., Chiper, M., Akasov, R., Anton, H., Messaddeq, N., Fournel, S., Klymchenko, A.S., Mely, Y., and Vandamme, T.F. (2014) Biodistribution of x-ray iodinated contrast agent in nano-emulsions is controlled by the chemical nature of the oily core. Acs Nano 8, 10537-10550.
- Anton, N., and Vandamme, T.F. (2014) Nanotechnology for computed tomography : A real potential recently disclosed. Pharm. Res. 31, 20-34.

Publications 2013

Liste des publications en 2013

- Attia, M. F., Anton, N., Chiper, M., Akasov, R., Anton, H., Messaddeq, N., Fournel, S., Klymchenko, A. S., Mely, Y., and Vandamme, T. F. (2014) Biodistribution of x-ray iodinated contrast agent in nano-emulsions is controlled by the chemical nature of the oily core. ACS nano 8, 10537-50.
- Weghofer, M., Grote, M., Resch, Y., Casset, A., Kneidinger, M., Kopec, J., Thomas, W. R., Fernandez-Caldas, E., Kabesch, M., Ferrara, R., Mari, A., Purohit, A., Pauli, G., Horak, F., Keller, W., Valent, P., Valenta, R., and Vrtala, S. (2013) Identification of Der p 23, a peritrophin-like protein, as a new major Dermatophagoides pteronyssinus allergen associated with the peritrophic matrix of mite fecal pellets. J. Immunol. 190, 3059-3067.
- Rydzek, G., Garnier, T., Schaaf, P., Voegel, J. C., Senger, B., Frisch, B., Haikel, Y., Petit, C., Schlatter, G., Jierry, L., and Boulmedais, F. (2013) Self-construction of supramolecular polyrotaxane films by an electrotriggered morphogen-driven process. Langmuir 29, 10776-10784.
- Reix, N., Sigrist, S., Heurtault, B., Agin, A., Moreau, F., Pinget, M., and Jeandidier, N. (2013) Glycemic management of diabetes by insulin therapy. Minerva Endocrinol. 38, 29-46.
- Reix, N., Massart, C., d’Herbomez, M., Gasser, F., Heurtault, B., and Agin, A. (2013) Thyroid-stimulating hormone and free thyroxine on the ADVIA Centaur immunoassay system : a multicenter assessment of analytical performance. Clin. Biochem. 46, 1305-8.
- Reisch, A., Tirado, P., Roger, E., Boulmedais, F., Collin, D., Voegel, J.-C., Frisch, B., Schaaf, P., and Schlenoff, J. (2013) Compact saloplastic poly(acrylic acid)/poly(allylamine) complexes : Kinetic control over composition, microstructure, and mechanical properties. Adv. Funct. Mater. 23, 673-682.
- Laverny, G., Casset, A., Purohit, A., Schaeffer, E., Spiegelhalter, C., de Blay, F., and Pons, F. (2013) Immunomodulatory properties of multi-walled carbon nanotubes in peripheral blood mononuclear cells from healthy subjects and allergic patients. Toxicol. Lett. 217, 91-101.
- Kastner, P. E., Le Calve, S., Zheng, W. Y., Casset, A., and Pons, F. (2013) A dynamic system for single and repeated exposure of airway epithelial cells to gaseous pollutants. Toxicol. Vitro 27, 632-640.
- Gentine, P., Bourel-Bonnet, L., and Frisch, B. (2013) Modified and derived ethanol injection toward liposomes : development of the process. J. liposome Res. 23, 11-9.
- Fend, L., Accart, N., Kintz, J., Cochin, S., Reymann, C., Le Pogam, F., Marchand, J. B., Menguy, T., Slos, P., Rooke, R., Fournel, S., Bonnefoy, J. Y., Preville, X., and Haegel, H. (2013) Therapeutic effects of anti-CD115 monoclonal antibody in mouse cancer models through dual inhibition of tumor-associated macrophages and osteoclasts. PLoS One 8, e73310.
- Casset, A., Valenta, R., and Vrtala, S. (2013) Allergen content and in vivo allergenic activity of house dust mite extracts. Int. Arch. allergy Immunol. 161, 287-8.
- Bohren, Y., Tessier, L. H., Megat, S., Petitjean, H., Hugel, S., Daniel, D., Kremer, M., Fournel, S., Hein, L., Schlichter, R., Freund-Mercier, M. J., Yalcin, I., and Barrot, M. (2013) Antidepressants suppress neuropathic pain by a peripheral beta2-adrenoceptor mediated anti-TNFalpha mechanism. Neurobiol. Dis. 60, 39-50.
- Barnig, C., Reboux, G., Roussel, S., Casset, A., Sohy, C., Dalphin, J. C., and de Blay, F. (2013) Indoor dust and air concentrations of endotoxin in urban and rural environments. Lett. Appl. Microbiol. 56, 161-7.
- Barnig, C., Purohit, A., Casset, A., Sohy, C., Lieutier-Colas, F., Sauleau, E., and de Blay, F. (2013) Nonallergic airway hyperresponsiveness and allergen-specific IgE levels are the main determinants of the early and late asthmatic response to allergen. J. Invest. Allerg. Clin. 23, 267-274.
- Tirado, P., Reisch, A., Roger, E., Boulmedais, F., Jierry, L., Lavalle, P., Voegel, J.-C., Schaaf, P., Schlenoff, J., and Frisch, B. (2013) Catalytic saloplastics : alkaline phosphatase immobilized and stabilized in compacted polyelectrolyte complexes. Adv. Funct. Mater. 23, 4785-4792.
- Smulski, C. R., Beyrath, J., Decossas, M., Chekkat, N., Wolff, P., Estieu-Gionnet, K., Guichard, G., Speiser, D., Schneider, P., and Fournel, S. (2013) Cysteine-rich domain 1 of CD40 mediates receptor self-assembly. J. Biol. Chem. 288, 10914-22.
- Lamanna, G., Smulski, C. R., Chekkat, N., Estieu-Gionnet, K., Guichard, G., Fournel, S., and Bianco, A. (2013) Multimerization of an apoptogenic TRAIL-mimicking peptide by using adamantane-based dendrons. Chemistry 19, 1762-8.
- Devarasu, T., Saad, R., Ouadi, A., Frisch, B., Robinet, E., Laquerriere, P., Voegel, J. C., Baumert, T., Ogier, J., and Meyer, F. (2013) Potent calcium phosphate nanoparticle surface coating for in vitro and in vivo siRNA delivery : a step toward multifunctional nanovectors. J. Mater. Chem. 1, 4692-4700.
- Bacharouche, J., Badique, F., Fahs, A., Spanedda, M. V., Geissler, A., Malval, J.P., Vallat, M. F., Anselme, K., Francius, G., Frisch, B., Hemmerle, J., Schaaf, P., and Roucoules, V. (2013) Biomimetic cryptic site surfaces for reversible chemo- and cyto-mechanoresponsive substrates. ACS nano 7, 3457-65.
- Pierrat, P., Laverny, G., Creusat, G., Wehrung, P., Strub, J. M., VanDorsselaer, A., Pons, F., Zuber, G., and Lebeau, L. (2013) Phospholipid-Detergent Conjugates as Novel Tools for siRNA Delivery. Chem-Eur J 19, 2344-2355.
- Pierrat, P., Kereselidze, D., Wehrung, P., Zuber, G., Pons, F., and Lebeau, L. (2013) Bioresponsive deciduouscharge amphiphiles for liposomal delivery of DNA and siRNA. Pharm. Res. 30, 1362-1379.
- Philippe, L., Alsaleh, G., Pichot, A., Ostermann, E., Zuber, G., Frisch, B., Sibilia, J., Pfeffer, S., Bahram, S., Wachsmann, D., and Georgel, P. (2013) MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes. Ann. Rheum. dis. 72, 1071-9.
- Lemoine, D., Habermacher, C., Martz, A., Mery, P.F., Bouquier, N., Diverchy, F., Taly, A., Rassendren, F., Specht, A., and Grutter, T. (2013) Optical control of an ion channel gate. Proc. Natl. Acad. Sci. U. S. A. 110, 20813-20818.
- Jiang, R., Taly, A., and Grutter, T. (2013) Moving through the gate in ATP-activated P2X receptors. Trends Biochem. Sci. 38, 20-29.
- Chataigneau, T., Lemoine, D., and Grutter, T. (2013) Exploring the ATP-binding site of P2X receptors. Front. Cell. Neurosci. 7, 273.
- Anton, N., Atzenhoffer, M., Daubeuf, F., Li, X., Schini-Kerth, V.B., Delmotte, B., Vandamme, T.F., and Chataigneau, T. (2013) Do iodinated nano-emulsions designed for preclinical vascular imaging alter the vascular reactivity in rat aorta ? Int. J. Pharm. 454, 143-148.
- Herbivo, C., Omran, Z., Revol, J., Javot, H., and Specht, A. (2013) Synthesis and characterization of cellpermeable caged phosphates that can be photolyzed by visible light or 800 nm two-photon photolysis. ChemBioChem 14, 2277-2283.
- Ftouni, H., Bolze, F., and Nicoud, J.-F. (2013) Water-soluble diketopyrrolopyrrole derivatives for two-photon excited fluorescence microscopy. Dyes Pigment. 97, 77-83.
- Ftouni, H., Bolze, F., de Rocquigny, H., and Nicoud, J.F. (2013) Functionalized two-photon absorbing diketopyrrolopyrrole-based fluorophores for living cells fluorescent microscopy. Bioconjugate Chem. 24, 942-950.
- Wandhammer, M., de Koning, M., van Grol, M., Loiodice, M., Saurel, L., Noort, D., Goeldner, M., and Nachon, F. (2013) A step toward the reactivation of aged cholinesterases—crystal structure of ligands binding to aged human butyrylcholinesterase. Chem.-Biol. Interact. 203, 19-23.
- Anton, N., Pierrat, P., Lebeau, L., Vandamme, T.F., and Bouriat, P. (2013) A study of insoluble monolayers by deposition at a bubble interface. Soft Matter 9, 10081-10091.
- Chandrashekhar, C., Pons, B., Muller, C. D., Tounsi, N., Mulherkar, R., and Zuber, G. (2013) Oligobenzylethylenimine enriches linear polyethylenimine with a pH-sensitive membrane-disruptive property and leads to enhanced gene delivery activity. Acta Biomater. 9, 4985-4993.
- Fenard, D., Genries, S., Scherman, D., Galy, A., Martin, S., and Kichler, A. (2013) Infectivity enhancement of different HIV-1-based lentiviral pseudotypes in presence of the cationic amphipathic peptide LAH4-L1. J. Virol. Methods 189, 375-378.
- Fenard, D., Ingrao, D., Seye, A., Buisset, J., Genries, S., Martin, S., Kichler, A., and Galy, A. (2013) Vectofusin-1, a new viral entry enhancer, strongly promotes lentiviral transduction of human hematopoietic stem cells. Mol. Ther. Nucleic Acids 2, e90.
- Guerra, S., Schillinger, F., Sigwalt, D., Holler, M., and Nierengarten, J.F. (2013) Synthesis of optically pure [60]fullerene e,e,e-tris adducts. Chem. Commun. 49, 4752-4754.
- Guerra, S., Trinh, T. M. N., Schillinger, F., Muhlberger, L., Sigwalt, D., Holler, M., and Nierengarten, J.F. (2013) The di-t-butylsilylene protecting group as a bridging unit in linear and macrocyclic bis-malonates for the regioselective multifunctionalization of C-60. Tetrahedron Lett. 54, 6251-6257.
- Kichler, A., Mason, A. J., Marquette, A., and Bechinger, B. (2013) Histidine-rich cationic amphipathic peptides for plasmid DNA and siRNA delivery. Methods Mol. Biol. 948, 85-103.
- Li, X., Anton, N., Zuber, G., Zhao, M., Messaddeq, N., Hallouard, F., Fessi, H., and Vandamme, T.F. (2013) Iodinated alpha-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging. Biomaterials 34, 481-91.
- Nierengarten, I., Nothisen, M., Sigwalt, D., Biellmann, T., Holler, M., Remy, J.S., and Nierengarten, J. F. (2013) Polycationic pillar[5]arene derivatives : interaction with DNA and biological applications. Chemistry 19, 17552-8.
- Perche, P., Nothisen, M., Bagilet, J., Behr, J.P., Kotera, M., and Remy, J.S. (2013) Cell-penetrating cationic siRNA and lipophilic derivatives efficient at nanomolar concentrations in the presence of serum and albumin. J. Control. Release 170, 92-8.
- Philippe, L., Alsaleh, G., Pichot, A., Ostermann, E., Zuber, G., Frisch, B., Sibilia, J., Pfeffer, S., Bahram, S., Wachsmann, D., and Georgel, P. (2013) MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes. Ann. Rheum. Dis. 72, 1071-1079.
- Pierrat, P., Kereselidze, D., Wehrung, P., Zuber, G., Pons, F., and Lebeau, L. (2013) Bioresponsive deciduous-charge amphiphiles for liposomal delivery of DNA and siRNA. Pharm. Res. 30, 1362-1379.
- Pierrat, P., Laverny, G., Creusat, G., Wehrung, P., Strub, J.-M., VanDorsselaer, A., Pons, F., Zuber, G., and Lebeau, L. (2013) Phospholipid-detergent conjugates as novel tools for siRNA delivery. Chem.-Eur. J. 19, 2344-2355.
- Schaeffer, E., Dehuyser, L., Sigwalt, D., Flacher, V., Bernacchi, S., Chaloin, O., Remy, J.S., Mueller, C.G., Baati, R., and Wagner, A. (2013) Dynamic micelles of mannoside glycolipids are more efficient than polymers for inhibiting HIV-1 trans-infection. Bioconjugate Chem. 24, 1813-1823.
- Sigwalt, D., Holler, M., and Nierengarten, J.F. (2013) A rigid macrocyclic bis-malonate for the regioselective preparation of trans-1 and trans-3 fullerene bis-adducts. Tetrahedron Lett. 54, 3160-3163.
- Sigwalt, D., Schillinger, F., Guerra, S., Holler, M., Berville, M., and Nierengarten, J.F. (2013) An expeditious regioselective synthesis of [60]fullerene e,e,e tris-adduct building blocks. Tetrahedron Lett. 54, 4241-4244.
- Lebeau, L., and Vénien-Bryan C. (2013) Monolayer two-dimensional crystallization of membrane proteins. In Methods in Molecular biology - Electron Crystallography of soluble and membrane proteins (Schmidt-Krey, I., and Cheng, Y. Eds, Humana Press), 955, 59-72.
- Vrignaud, S., Anton, N., Passirani, C., Benoit, J.P., and Saulnier, P. (2013) Aqueous core nanocapsules : a new solution for encapsulating doxorubicin hydrochloride. Drug Dev. Indust. Pharm. 39, 1706-1711.
- Supper, S., Anton, N., Seidel, N., Riemenschnitter, M., Schoch, C., and Vandamme, T.F. (2013) Rheological study of chitosan/polyol-phosphate systems : Influence of the polyol part on the thermo-induced gelation mechanism. Langmuir 29, 10229-10237.
- Serra, C.A., Khan, I.U., Chang, Z., Bouquey, M., Muller, R., Kraus, I., Schmutz, M., Vandamme, T.F., Anton, N., Ohm, C., Zentel, R., Knauer, A., and Koehler, M. (2013) Engineering polymer microparticles by droplet microfluidics. J. Flow Chem. 3, 66-75.
- Serra, C.A., Cortese, B., Khan, I.U., Anton, N., de Croon, M.H.J.M., Hessel, V., Ono, T., and Vandamme, T.F. (2013) Coupling microreaction technologies, polymer chemistry, and processing to produce polymeric micro and nanoparticles with controlled size, morphology, and composition. Macromol. React. Eng. 7, 414-439.
- Phuc Nghia, N., Waton, G., Vandamme, T., and Krafft, M.P. (2013) Reversing the course of the competitive adsorption between a phospholipid and albumin at an air-water interface. Soft Matter 9, 9972-9976.
- Phuc Nghia, N., Waton, G., Vandamme, T.F., and Krafft, M.P. (2013) Behavior of an adsorbed phospholipid monolayer submitted to prolonged periodical surface Density variations. Angew. Chem. Int. Ed. Engl. 52, 6404-6408.
- Li, X., Anton, N., Zuber, G., Zhao, M., Messaddeq, N., Hallouard, F., Fessi, H., and Vandamme, T.F. (2013) Iodinated alpha-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging. Biomaterials 34, 481-491.
- Khan, I.U., Serra, C.A., Anton, N., and Vandamme, T.F. (2013) Continuous-flow encapsulation of ketoprofen in copolymer microbeads via co-axial microfluidic device : Influence of operating and material parameters on drug carrier properties. Int. J. Pharm. 441, 809-817.
- Khan, I.U., Serra, C.A., Anton, N., and Vandamme, T.F. (2013) Microfluidics : A focus on improved cancer targeted drug delivery systems. J. Control. Release 172, 1065-1074.
- Hallouard, F., Briancon, S., Anton, N., Li, X., Vandamme, T.F., and Fessi, H. (2013) Iodinated nano-emulsions as contrast agents for preclinical X-ray imaging : Impact of the free surfactants on the pharmacokinetics. Eur. J. Pharm. Biopharm. 83, 54-62.
- Hallouard, F., Briancon, S., Anton, N., Li, X., Vandamme, T.F., and Fessi, H. (2013) Poly(ethylene glycol)- poly(epsilon-caprolactone) iodinated nanocapsules as contrast agents for x-ray imaging. Pharm. Res. 30, 2023-2035.
- Korovitch, A., Le Roux, A., Barbault, F., Hemadi, M., Ha-Duong, N.T., Lion, C., Wagner, A., and El Hage Chahine, J.M. (2013) A new series of Cs+, K+ and Na+ chelators : synthesis, kinetics, thermodynamics and modeling. Inorg. Chim. Acta 394, 45-57.
- Schaeffer, E., Dehuyser, L., Sigwalt, D., Flacher, V., Bernacchi, S., Chaloin, O., Remy, J.S., Mueller, C.G., Baati, R., and Wagner, A. (2013) Dynamic micelles of mannoside glycolipids are more efficient than polymers for inhibiting HIV-1 trans-infection. Bioconjugate Chem. 24, 1813-1823.
- Koniev, O., Leriche, G., Nothisen, M., Remy, J.S., Strub, J.M., Schaeffer-Reiss, C., Van Dorsselaer, A., Baati, R., and Wagner, A. (2013) Selective irreversible chemical tagging of cysteine with 3-arylpropiolonitriles. Bioconjugate Chem. 25, 202–206.
- Kuhn, I., Kellenberger, E., Schuber, F., and Muller-Steffner, H. (2013) Schistosoma mansoni NAD(+) catabolizing enzyme : Identification of key residues in catalysis. Biochim. Biophys. Acta 1834, 2520-2527.

Publications 2012

Liste des publications en 2012

- Donato, L., Mourot, A., Davenport, C.M., Herbivo, C., Warther, D., Leonard, J., Bolze, F., Nicoud, J.F., Kramer, R.H., Goeldner, M., and Specht, A. (2012) Water-soluble, donor-acceptor biphenyl derivatives in the 2-(o-nitrophenyl)propyl series : Highly efficient two-photon uncaging of the neurotransmitter g-aminobutyric acid at 800 nm. Ang. Chem. Int. Ed. Engl. 51, 1840-1843.
- Loerinczi, E., Bhargava, Y., Marino, S.F., Taly, A., Kaczmarek-Hajek, K., Barrantes-Freer, A., Dutertre, S., Grutter, T., Rettinger, J., and Nicke, A. (2012) Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor. Proc. Natl. Acad. Sci. U. S. A. 109, 11396-11401.
- Lemoine, D., Jiang, R., Taly, A., Chataigneau, T., Specht, A., and Grutter, T. (2012) Ligand-gated ion channels : New insights into neurological disorders and ligand recognition. Chem. Rev. 112, 6285-6318.
- Jiang, R., Taly, A., Lemoine, D., Martz, A., Specht, A., and Grutter, T. (2012) Intermediate closed channel state(s) precede(s) activation in the ATP-gated P2X2 receptor. Channels 6, 398-402.
- Specht, A., Bolze, F., Donato, L., Herbivo, C., Charon, S., Warther, D., Gug, S., Nicoud, J.F., and Goeldner, M. (2012) The donor-acceptor biphenyl platform : Aversatile chromophore for the engineering of highly efficient two-photon sensitive photoremovable protecting groups. Photochem. Photobiol. Sci. 11, 578-586.
- Bolze, F., Nicoud, J.F., Bourgogne, C., Gug, S., Sun, X.H., Goeldner, M., Specht, A., Donato, L., Warther, D., Turi, G.F., and Losonczy, A. (2012) Two-photon uncaging : The chemist point of view. Opt. Mater. 34, 1664- 1669.
- Jiang, R., Taly, A., Lemoine, D., Martz, A., Cunrath, O., and Grutter, T. (2012) Tightening of the ATP-binding sites induces the opening of P2X receptor channels. EMBO J. 31, 2134-2143.
- Lux, J., Pena, E.J., Bolze, F., Heinlein, M., and Nicoud, J.F. (2012) Malachite green derivatives for twophoton RNA detection. ChemBioChem 13, 1206-1213.
- Lovett-Barron, M., Turi, G. F., Kaifosh, P., Lee, P. H., Bolze, F., Sun, X.-H., Nicoud, J.F., Zemelman, B. V., Sternson, S.M., and Losonczy, A. (2012) Regulation of neuronal input transformations by tunable dendritic inhibition. Nature Neurosci. 15, 423-U111.
- Behr, J.P. (2012) Synthetic gene transfer vectors II : Back to the future. Acc. Chem. Res. 45, 980-984.
- Creusat, G., Thomann, J.S., Maglott, A., Pons, B., Dontenwill, M., Guerin, E., Frisch, B., and Zuber, G. (2012) Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo. J. Control. Release 157, 418-26.
- Gerard, X., Perrault, I., Hanein, S., Silva, E., Bigot, K., Defoort-Delhemmes, S., Rio, M., Munnich, A., Scherman, D., Kaplan, J., Kichler, A., and Rozet, J.M. (2012) AON-mediated exon skipping restores ciliation in fibroblasts harboring the common Leber congenital amaurosis CEP290 mutation. Mol. Ther. Nucleic Acids 1, e29.
- Guiraud, S., van Wittenberghe, L., Georger, C., Scherman, D., and Kichler, A. (2012) Identification of decorin derived peptides with a zinc dependent anti-myostatin activity. Neuromuscul. Disord. 22, 1057-68.
- Iacobucci, V., Di Giuseppe, F., Bui, T. T., Vermeer, L. S., Patel, J., Scherman, D., Kichler, A., Drake, A. F., and Mason, A. J. (2012) Control of pH responsive peptide self-association during endocytosis is required for effective gene transfer. Biochim. Biophys. Acta 1818, 1332-41.
- Paris, C., Moreau, V., Deglane, G., Karim, L., Couturier, B., Bonnet, M.-E., Kedinger, V., Messmer, M., Bolcato-Bellemin, A.-L., Behr, J.P., Erbacher, P., and Lenne-Samuel, N. (2012) Conjugating phosphospermines to siRNAs for improved stability in serum, intracellular delivery and RNAi-mediated gene silencing. Mol. Pharm. 9, 3464-3475.
- Pierrat, P., Creusat, G., Laverny, G., Pons, F., Zuber, G., and Lebeau, L. (2012) A cationic phospholipiddetergent conjugate as a new efficient carrier for siRNA delivery. Chem.-Eur. J. 18, 3835-3839.
- Ronzani, C., Spiegelhalter, C., Vonesch, J.L., Lebeau, L., and Pons, F. (2012) Lung deposition and toxicological responses evoked by multi-walled carbon nanotubes dispersed in a synthetic lung surfactant in the mouse. Arch. Toxicol. 86, 137-149.
- Wintgens, V., Leborgne, C., Baconnais, S., Burckbuchler, V., Le Cam, E., Scherman, D., Kichler, A., and Amiel, C. (2012) Smart DNA vectors based on cyclodextrin polymers : compaction and endosomal release. Pharm. Res. 29, 384-96.
- Yu, T., Liu, X., Bolcato-Bellemin, A. L., Wang, Y., Liu, C., Erbacher, P., Qu, F., Rocchi, P., Behr, J.P., and Peng, L. (2012) An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo. Angew. Chem. Int. Ed. Engl. 51, 8478-8484.
- Kaaki, K., Hervé, K., Chiper, M., Shkilnyy, A., Soucé, M., Benoit, R., Paillard, A., Dubois, P., Saboungi, M.L., Chourpa, I. (2012) Magnetic nanocarriers of doxorubicin coated with poly(ethylene glycol) and folic acid : relation between coating structure, surface properties, colloidal stability and cancer cell targeting. Langmuir 28, 1496-1505.
- Creusat, G., Thomann, J.S., Maglott, A., Pons, B., Dontenwill, M., Guérin, E., Frisch, B., and Zuber, G. (2012) Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo. J. Control. Release 157, 418-426.
- Pierrat, P., Creusat, G., Laverny, G., Pons, F., Zuber, G., and Lebeau, L. (2012) A cationic phospholipiddetergent conjugate as a new efficient carrier for siRNA delivery. Chemistry 18, 3835-3839.
- Souilem, I., Muller, R., Holl, Y., Bouquey, M., Serra, C.A., Vandamme, T.F., and Anton, N. (2012) A Novel Low-Pressure Device for Production of Nanoemulsions. Chem. Eng. Technol. 35, 1692-1698.
- Schante, C.E., Zuber, G., Herlin, C., and Vandamme, T.F. (2012) Improvement of hyaluronic acid enzymatic stability by the grafting of amino-acids. Carbohydr. Polym. 87, 2211-2216.
- Qusaj, Y., Leng, A., Alshihabi, F., Krasniqi, B., and Vandamme, T.F. (2012) Development strategies for herbal products reducing the influence of natural variance in dry mass on tableting properties and tablet characteristics. Pharmaceutics 4, 501-516.
- Klymchenko, A.S., Roger, E., Anton, N., Anton, H., Shulov, I., Vermot, J., Mely, Y., and Vandamme, T.F. (2012) Highly lipophilic fluorescent dyes in nano-emulsions : towards bright non-leaking nano-droplets. RSC Adv. 2, 11876-11886.
- Jakhmola, A., Anton, N., and Vandamme, T.F. (2012) Inorganic nanoparticles based contrast agents for x-ray computed tomography. Adv. Healthcare Mater. 1, 413-431.
- Gbassi, G.K., and Vandamme, T.F. (2012) Probiotic encapsulation technology : From microencapsulation to release into the gut. Pharmaceutics 4, 149-163.
- Bally, F., Garg, D.K., Serra, C.A., Hoarau, Y., Anton, N., Brochon, C., Parida, D., Vandamme, T.F., and Hadziioannou, G. (2012) Improved size-tunable preparation of polymeric nanoparticles by microfluidic nanoprecipitation. Polymer 53, 5045-5051.
- Anton, N., Jakhmola, A., and Vandamme, T.F. (2012) Trojan microparticles for drug delivery. Pharmaceutics 4, 1-25.
- Anton, N., de Crevoisier, A., Schmitt, S., and Vandamme, T.F. (2012) A new application of lipid nanoemulsions as coating agent, providing zero-order hydrophilic drug release from tablets. J. Drug Deliv. 2012, 271319-271319.
- Anton, N., Bally, F., Serra, C. A., Ali, A., Arntz, Y., Mely, Y., Zhao, M., Marchioni, E., Jakhmola, A., and Vandamme, T.F. (2012) A new microfluidic setup for precise control of the polymer nanoprecipitation process and lipophilic drug encapsulation. Soft Matter 8, 10628-10635.
- Alshihabi, F., Vandamme, T.F., and Betz, G. (2012) Predicting physical properties of pharmaceutical compacts using focused beam reflectance measurement (FBRM). J. Drug Deliv. Sci. Technol. 22, 522-530.
- Vrignaud, S., Anton, N., Gayet, P., Benoit, J.P., and Saulnier, P. (2011) Reverse micelle-loaded lipid nanocarriers : A novel drug delivery system for the sustained release of doxorubicin hydrochloride. Eur. J. Pharm. Biopharm. 79, 197-204.
- Egea, P.F., Muller-Steffner, H., Kuhn, I., Cakir-Kiefer, C., Oppenheimer, N.J., Stroud, R.M., Kellenberger, E., and Schuber, F. (2012) Insights into the mecanism of bovine CD38/NAD+glycohydrolase from X-ray stuctures of its mickaelis complex and covalently-trapped intermediates. PLoS One 7, e34918.
- Leriche, G., Chisholm, L., Wagner, A. (2012) Cleavable linkers in chemical biology. Bioorg. Med. Chem. 20, 571-5082.
- Bui The Thuong, M., Catala, C., Colas, C., Schaeffer, C., Van Dorsselaer, A., Mann, A., and Wagner, A. (2012) Trimethoxyarene, a Highly Ionisable Tag for Reaction Analysis by APPI/MS : Exploration of Heterocyclic. Synthesis. Eur. J. Org. Chem., 85-92.
- Bui The Thuong, M., Mann, A., and Wagner, A. (2012) Mild chemo-selective hydration of terminal alkynes catalyzed by AgSbF6. Chem. Commun. 48, 434-436.
- Leriche, G., Budin, G., Darwich, Z., Weltin, D., Mély, Y., Klymchenko, A.S., and Wagner, A. (2012) A FRET based probe with a chemically deactivatable quencher. Chem. Commun. 48, 3224-3226
- Varenne, F., Bourdillon, M., Meyer, M., Lin, Y., Brellier, M., Baati, R., Charbonnière, L.J., Wagner, A., Doris, E., Taran, F., and Hagège, A. (2012) Capillary electrophoresis–inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands. J. Chromatogr. A 1229, 280–287.
- Dehuyser, L., Schaeffer, E., Chaloin, O., Mueller, C.G., Baati, R., and Wagner, A. (2012) Synthesis of novel mannoside glycolipid conjugates for inhibition of HIV-1 trans-infection. Bioconjugate Chem. 23, 1731–1739.
- King, M., Baati, R., and Wagner, A. (2012) New tetramethylthiepinium (TMTI) for copper-free click chemistry. Chem. Commun. 48, 9308–9309.
- De Talance, V.L., Massinon, O., Baati, R., Wagner, A., and Vincent, S.P. (2012) First steps towards conformationally selective artificial lectins : The chair-boat discrimination by molecularly imprinted polymers. Chem. Commun. 48, 10684-10686.
- Lebon, F., Pegurier, C., Ledecq, M., Mathieu, B., Bosman, N, Frycia, A., Lengele, S., Dhurke, K., Ananda, K.K., Meunier, S., Wagner, A., and Provins, L. (2012) Towards a KCC2 blocker pharmacophore model. Bioorg. Med. Chem. Lett. 22, 3978-3982.
- Rydzek, G., Polavarapu, P., Rios, C., Tisserant, J. N., Voegel, J. C., Senger, B., Lavalle, P., Frisch, B., Schaaf, P., Boulmedais, F., and Jierry, L. (2012) Morphogen-driven self-construction of covalent films built from polyelectrolytes and homobifunctional spacers : buildup and pH response. Soft Matter. 8, 10336-10343.
- Rydzek, G., Parat, A., Polavarapu, P., Baehr, C., Voegel, J. C., Hemmerle, J., Senger, B., Frisch, B., Schaaf, P., Jierry, L., and Boulmedais, F. (2012) One-pot morphogen driven self-constructing films based on noncovalent host-guest interactions. Soft Matter. 8, 446-453.
- Ronzani, C., Spiegelhalter, C., Vonesch, J. L., Lebeau, L., and Pons, F. (2012) Lung deposition and toxicological responses evoked by multi-walled carbon nanotubes dispersed in a synthetic lung surfactant in the mouse. Arch. Toxicol. 86, 137-149.
- Reix, N., Massart, C., Gasser, F., Heurtault, B., and Agin, A. (2012) Should functional sensitivity of a new thyroid stimulating hormone immunoassay be monitored routinely ? The ADVIA Centaur TSH3-UL assay experience. Clin. Biochem. 45, 1260-2.
- Ivanov, S., Fontaine, J., Paget, C., Fernandez, E. M., Van Maele, L., Renneson, J., Maillet, I., Wolf, N. M., Rial, A., Leger, H., Ryffel, B., Frisch, B., Chabalgoity, J. A., Sirard, J. C., Benecke, A., Faveeuw, C., and Trottein, F. (2012) Key role for respiratory CD103(+) dendritic cells, IFN-gamma, and IL-17 in protection against Streptococcus pneumoniae infection in response to alpha-galactosylceramide. J. Infect. Dis. 206, 723- 734.
- Gentine, P., Bubel, A., Crucifix, C., Bourel-Bonnet, L., and Frisch, B. (2012) Manufacture of liposomes by isopropanol injection : characterization of the method. J. Liposome Res. 22, 18-30.
- Casset, A., Mari, A., Purohit, A., Resch, Y., Weghofer, M., Ferrara, R., Thomas, W. R., Alessandri, C., Chen, K. W., de Blay, F., Valenta, R., and Vrtala, S. (2012) Varying allergen composition and content affects the in vivo allergenic activity of commercial Dermatophagoides pteronyssinus extracts. Int. Arch. Allergy Immunol. 159, 253-262.
- Becker, J., Delayre-Orthez, C., Frossard, N., and Pons, F. (2012) The peroxisome proliferator-activated receptor alpha agonist fenofibrate decreases airway reactivity to methacholine and increases endothelial nitric oxide synthase phosphorylation in mouse lung. Fund. Clin. Pharmacol. 26, 340-346.
- Barnig, C., and Casset, A. (2012) Respiratory allergens and asthma exacerbation. Rev. Mal. Respir. 29, 810-819.
- Thomann, J.S., Monneaux, F., Creusat, G., Spanedda, M.V., Heurtault, B., Habermacher, C., Schuber, F., Bourel-Bonnet, L., and Frisch, B. (2012) Novel glycolipid TLR2 ligands of the type Pam2Cys-alpha-Gal : synthesis and biological properties. Eur. J. Med. Chem. 51, 174-83.
- Roger, E., Kalscheuer, S., Kirtane, A., Guru, B. R., Grill, A. E., Whittum-Hudson, J., and Panyam, J. (2012) Folic acid functionalized nanoparticles for enhanced oral drug delivery. Mol. Pharm. 9, 2103-2110.
- Macho Fernandez, E., Chang, J., Fontaine, J., Bialecki, E., Rodriguez, F., Werkmeister, E., Krieger, V., Ehret, C., Heurtault, B., Fournel, S., Frisch, B., Betbeder, D., Faveeuw, C., and Trottein, F. (2012), Activation of invariant Natural Killer T lymphocytes in response to the alpha-galactosylceramide analogue KRN7000 encapsulated in PLGA-based nanoparticles and microparticles. Int. J. Pharm. 423, 45-54.
- Estieu-Gionnet, K., Odaert, B., Smulski, C., Pavet, V., Fournel, S., Gronemeyer, H., and Guichard, G. (2012) Desulfurisation of a cyclic peptide targeting Death Receptor 5 : Conformational outcome and consequences on biological properties. J. Pept. Sci. 18, S104-S104.
- Davila, J., Chassepot, A., Longo, J., Boulmedais, F., Reisch, A., Frisch, B., Meyer, F., Voegel, J. C., Mesini, P. J., Senger, B., Metz-Boutigue, M. H., Hemmerle, J., Lavalle, P., Schaaf, P., and Jierry, L. (2012) Cytomechanoresponsive polyelectrolyte multilayer films. J. Am. Chem. Soc. 134, 83-86.
- Chassepot, A., Gao, L.C., Nguyen, I., Dochter, A., Fioretti, F., Menu, P., Kerdjoudj, H., Baehr, C., Schaaf, P., Voegel, J.C., Boulmedais, F., Frisch, B., and Ogier, J. (2012) Chemically detachable polyelectrolyte multilayer platform for cell sheet engineering. Chem. Mater. 24, 930-937.
- Pierrat, P., Creusat, G., Laverny, G., Pons, F., Zuber, G., and Lebeau, L. (2012) A cationic phospholipiddetergent conjugate as a new efficient carrier for siRNA delivery. Chem.-Eur. J. 18, 3835-3839.
- Creusat, G., Thomann, J.S., Maglott, A., Pons, B., Dontenwill, M., Guerin, E., Frisch, B., and Zuber, G. (2012) Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo. J. Control. Release 157, 418-426.
- Chardon, E., Puleo, G. L., Dahm, G., Fournel, S., Guichard, G., and Bellemin-Laponnaz, S. (2012) Easy derivatisation of group 10 N-heterocyclic carbene complexes and in vitro evaluation of an anticancer oestradiol conjugate. ChemPlusChem 77, 1028-1038.