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Publications in 2011

- Bechinger, B., Vidovic, V., Bertani, P., and Kichler, A. (2011) A new family of peptide-nucleic acid nanostructures with potent transfection activities. J. Pept. Sci. 17, 88-93.
- Bialecki, E., Fernandez, E.M., Ivanov, S., Paget, C., Fontaine, J., Rodriguez, F., Lebeau, L., Ehret, C., Frisch, B., Trottein, F., and Faveeuw, C. (2011) Spleen-resident CD4(+) and CD4(-) CD8 alpha(-) dendritic cell subsets differ in their ability to prime invariant Natural Killer T lymphocytes. Plos One 6, e26919.
- Brissault, B., Leborgne, C., Scherman, D., Guis, C., and Kichler, A. (2011) Synthesis of poly(propylene glycol)-block-polyethylenimine triblock copolymers for the delivery of nucleic acids. Macromol. Biosci. 11, 652-61.
- Diaz, D.D., Morin, E., Schon, E.M., Budin, G., Wagner, A., and Remy, J.S. (2011) Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling. J. Mater. Chem. 21, 641-644.
- Erbacher, P., Moreau, V., Paris, C., Deglane, G., Couturier, B., Bellemin, A.L., Bonnet, M.E., Remy, J.S., Behr, J.P., and Lenne, N. (2011) Self-delivering cationic siRNAs mediate efficient and specific gene silencing in human cells. Nucl. Acid Ther. 21, A7-A7.
- Foillard, S., Zuber, G., and Doris, E. (2011) Polyethylenimine-carbon nanotube nanohybrids for siRNAmediated gene silencing at cellular level. Nanoscale 3, 1461-4.
- Guiraud, S., Alimi-Guez, D., van Wittenberghe, L., Scherman, D., and Kichler, A. (2011) The reverse block copolymer Pluronic 25R2 promotes DNA transfection of skeletal muscle. Macromol. Biosci. 11, 590-4.
- Liu, X., Wu, J., Yammine, M., Zhou, J., Posocco, P., Viel, S., Liu, C., Ziarelli, F., Fermeglia, M., Pricl, S., Victorero, G., Nguyen, C., Erbacher, P., Behr, J.P., and Peng, L. (2011) Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus. Bioconjugate Chem. 22, 2461-73.
- Morin, E., Nothisen, M., Wagner, A., and Remy, J.S. (2011) Cationic polydiacetylene micelles for gene delivery. Bioconjugate Chem. 22, 1916-1923.
- Perche, P., Kotera, M., and Remy, J.S. (2011) MMT, Npeoc-protected spermine, a valuable synthon for the solid phase synthesis of oligonucleotide oligospermine conjugates via guanidine linkers. Bioorg. Med. Chem. 19, 1972-1977.
- Sigwalt, D., Holler, M., Iehl, J., Nierengarten, J.F., Nothisen, M., Morin, E., and Remy, J.S. (2011) Gene delivery with polycationic fullerene hexakis-adducts. Chem. Commun. 47, 4640-4642.
- Wasungu, L., Marty, A. L., Bureau, M. F., Kichler, A., Bessodes, M., Teissie, J., Scherman, D., Rols, M.P., and Mignet, N. (2011) Pre-treatment of cells with pluronic L64 increases DNA transfection mediated by electrotransfer. J Control. Release 149, 117-25.
- Vrignaud, S., Anton, N., Gayet, P., Benoit, J.P., and Saulnier, P. (2011) Reverse micelle-loaded lipid nanocarriers : A novel drug delivery system for the sustained release of doxorubicin hydrochloride. Eur. J. Pharm. Biopharm. 79, 197-204.
- Schante, C.E., Zuber, G., Herlin, C., and Vandamme, T.F. (2011) Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications. Carbohydr. Polym. 85, 469-489.
- Schante, C.E., Zuber, G., Herlin, C., and Vandamme, T.F. (2011) Synthesis of N-alanyl-hyaluronamide with high degree of substitution for enhanced resistance to hyaluronidase-mediated digestion. Carbohydr. Polym. 86, 747-752.
- Phuc Nghia, N., Thuan Thao Trinh, D., Waton, G., Vandamme, T.F., and Krafft, M.P. (2011) A nonpolar, nonamphiphilic molecule can accelerate adsorption of phospholipids and lower their surface tension at the air/water interface. ChemPhysChem 12, 2646-2652.
- Li, X., Anton, N., Thi Minh Chau, T., Zhao, M., Messaddeq, N., and Vandamme, T.F. (2011) Microencapsulation of nanoemulsions : novel Trojan particles for bioactive lipid molecule delivery. Int. J. Nanomed. 6, 1313-1325.
- Hallouard, F., Anton, N., Zuber, G., Choquet, P., Li, X., Arntz, Y., Aubertin, G., Constantinesco, A., and Vandamme, T.F. (2011) Radiopaque iodinated nano-emulsions for preclinical X-ray imaging. RSC Adv. 1, 792-801.
- Gbassi, G.K., Vandamme, T.F., Yolou, F.S., and Marchioni, E. (2011) In vitro effects of pH, bile salts and enzymes on the release and viability of encapsulated Lactobacillus plantarum strains in a gastrointestinal tract model. Int. Dairy J. 21, 97-102.
- Bally, F., Serra, C. A., Brochon, C., Anton, N., Vandamme, T.F., and Hadziioannou, G. (2011) A continuousflow polymerization microprocess with online GPC and inline polymer recovery by micromixer-assisted nanoprecipitation. Macromol. React. Eng. 5, 542-547.
- Foillard, S., Zuber, G., and Doris, E. (2011) Polyethylenimine-carbon nanotube nanohybrids for siRNAmediated gene silencing at cellular level. Nanoscale 3, 1461-1464.
- Alshihabi, F., Vandamme, T.F., and Betz, G. (2011) Focused beam reflectance method as an innovative (PAT) tool to monitor in-line granulation process in fluidized bed. Pharm. Dev. Tech., 1-12.
- Anton, N., and Vandamme, T.F. (2011) Nano-emulsions and micro-emulsions : Clarifications of the critical differences. Pharm. Res. 28, 978-985.
- Kellenberger, E., Kuhn, I., Schuber, F., and Muller-Steffner, H. (2011) Flavonoids as inhibitors of human CD38. Bioorg. Med. Chem. Lett. 21, 3939-3942.
- Perino, A., Klymchenko, A., Morere, A., Contal, E., Rameau, A., Guenet, J.M., Mély, Y., and Wagner, A. (2011) Structure and behaviour of polydiacetylene-based micelles Macromol. Chem. Phys. 212, 111-117.
- Díaz Díaz, A., Morin, M., Schön, E.M., Budin, G., Wagner, A., and Remy, J.S. (2011) Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling. J. Mater. Chem. 21, 641-644.
- Contal, E., Klymchenko, A.S., Mely, Y., Meunier, S., and Wagner, A. (2011) Core functionalization of polydiacetylene micelles by "click" reaction Soft Matter 7, 1648-1650.
- Goncalves, S., Santoro, S., Nicolas, M., Wagner, A., Maillos, P., Himo, F., and Baati, R. (2011) Cationic cyclization of 2-alkenyl-1,3-dithiolanes : Diastereoselective synthesis of trans-decalins J. Org. Chem. 76, 3274-3285.
- Le Roux, A., Meunier, S., Le Gall, T., Denis, J.M., Bischoff, P., and Wagner, A. (2011) Synthesis and radioprotective properties of pulvinic acid derivatives ChemMedChem. 6, 561-569.
- Thauvin, C., Perino, A., Contal, E., Morin, E., Schultz, P., Meunier, S., and Wagner, A. (2011) Programmed dispersions of MWNTs in aqueous media by coating with photopolymerizable synthetic amphiphiles. J. Phys. Chem. C 115, 7319–7322.
- Mercey, G., Verdelet, T., Saint-André, G., Gillon, E., Wagner, A., Baati, R., Jean, L., Nachon, F., and Renard, P.Y. (2011) First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase Chem. Commun. 47, 5295-5297.
- Hoonakker, F., Varnek, A., Lachiche, N., and Wagner, A. (2011) A representation to apply usual data mining techniques to chemical reactions — Illustration on the rate constant of SN2 reactions in water. Int. J. Artif. Intell. Tools 20, 253-270.
- Saint-Andre, G., Kliachyna, M., Kodepelly, S., Louise-Leriche, L., Gillon, E., Renard, P.Y., Nachon, F., Baati, R., and Wagner, A. (2011) Design, synthesis and evaluation of new α-nucleophiles for the hydrolysis of organophosphorus nerve agents : application to the reactivation of phosphorylated acetylcholinesterase. Tetrahedron 67, 6352-6361.
- Francesco, I.N., Egloff, C., Wagner, A., and Colobert, F. (2011) Stereoselective addition of Grignard reagents to new P-chirogenic N-phosphinoylbenzaldimines : Effect of the phosphorus substituents on the stereoselectivity. Eur. J. Org. Chem., 20-21.
- Le Roux, A., Kuzmanovski, I. Habrant, D., Meunier, S., Bischoff, P., Thetiot-Laurent, S., Le Gall, T., Wagner, A., and Novic, M. (2011) Design and synthesis of new antioxidants predicted by the model developed on a set of pulvinic acid derivative. J. Chem. Inf. Model. 51, 3050–3059.
- Papillon, J., Potier, N., Crucifix, C. , Menetret, J.F. , Genet, C., Oudet, P., Wagner, A., Schultz, P., and Lamour, V. (2011) Structure/function studies of DNA gyrase supramolecular complexes. FEBS J. 1, 278, 472-472.
- Perino, A., Schmutz, M., Meunier, S., Mésini, P., and Wagner, A. (2011) Self-assembled nanotubes and helical tapes from diacetylene nonionic amphiphiles. Structural studies before and after polymerization. Langmuir 27, 12149–12155.
- Morin, E., Nothisen, M, Wagner, A., and Remy, J.S. (2011) Cationic polydiacetylene micelles for gene delivery. Bioconjugate Chem. 22, 1916–1923.
- Rydzek, G., Jierry, L., Parat, A., Thomann, J.S., Voegel, J. C., Senger, B., Hemmerle, J., Ponche, A., Frisch, B., Schaaf, P., and Boulmedais, F. (2011) Electrochemically triggered assembly of films : A one-pot morphogen-driven buildup. Angew. Chem. Int. Ed. Engl. 50, 4374-4377.
- Ronzani, C., Casset, A., and Pons, F. (2011) Effect of multi-walled carbon nanotubes on lung inflammation and systemic immune response in murine asthma models. Toxicol. Lett. 205, S288-S288.
- Pons, F., Laverny, G., Purohit, A., De Blay, F., and Casset, A. (2011) Immunomodulatory properties of multiwalled carbon nanotubes in peripheral blood mononuclear cells. Toxicol. Lett. 205, S286-S287.
- Laverny, G., Casset, A., Purohit, A., de Blay, F., and Pons, F. (2011) Effects of carbon nanotubes on cytokine secretion by peripheral blood mononuclear cells from healthy subjects and allergic patients. Inflamm. Res. 60, 175-176.
- Kastner, P.E., Le Calve, S., Casset, A., Zheng, W., and Pons, F. (2011) Exposure of airway epithelial cells in culture to a mixture of gaseous pollutants : Impact on cell integrity. Toxicol. Lett. 205, S123-S123.
- Kastner, P.E., Casset, A., and Pons, F. (2011) Formaldehyde interferes with airway epithelium integrity and functions in a dose- and time-dependent manner. Toxicol. Lett. 200, 109-116.
- Hilbold, B., Perrault, M., Ehret, C., Niu, S. L., Frisch, B., Pecheur, E. I., and Bourel-Bonnet, L. (2011) Benzophenone-containing fatty acids and their related photosensitive fluorescent new probes : Design, physicochemical properties and preliminary functional investigations. Bioorg. Med. Chem. Lett. 19, 7464-7473.
- Greiner, V.J., Shvadchak, V., Fritz, J., Arntz, Y., Didier, P., Frisch, B., Boudier, C., Mely, Y., and de Rocquigny, H. (2011) Characterization of the mechanisms of HIV-1 Vpr(52-96) internalization in cells. Biochimie 93, 1647-1658.
- Ferrara, R., Palazzo, P., Alessandri, C., Casset, A., Liso, M., Scala, E., Valenta, R., Vrtala, S., and Mari, A. (2011) Detection of Der p 1, Der p 2, Der f 1, Der f 2, and Der p 10 in commercial D. farinae and D. pteronyssinus extracts by single point highest inhibition achievable assay. Allergy 66, 322-322.
- Casset, A., and Braun, J.J. (2011) Relationships between indoor allergens, sensitization, and allergic asthma and rhinitis symptoms. Rev. Fr. Allergol. 51, 104-110.
- Boeglin, E., Smulski, C. R., Brun, S., Milosevic, S., Schneider, P., and Fournel, S. (2011) Toll-Like Receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells. PLoS One 6, e25542.
- Bialecki, E., Fernandez, E. M., Ivanov, S., Paget, C., Fontaine, J., Rodriguez, F., Lebeau, L., Ehret, C., Frisch, B., Trottein, F., and Faveeuw, C. (2011) Spleen-Resident CD4(+) and CD4(-) CD8 alpha(-) Dendritic Cell Subsets Differ in Their Ability to Prime Invariant Natural Killer T Lymphocytes. PLoS One 6, e26919.
- Thomann, J.S., Heurtault, B., Weidner, S., Braye, M., Beyrath, J., Fournel, S., Schuber, F., and Frisch, B. (2011) Antitumor activity of liposomal ErbB2/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting. Biomaterials 32, 4574-83.
- Roger, E., Lagarce, F., and Benoit, J.P. (2011) Development and characterization of a novel lipid nanocapsule formulation of Sn38 for oral administration. Eur. J. Pharm. Biopharm. 79, 181-188.
- Schini-Kerth, V.B., Etienne-Selloum, N., Chataigneau, T., and Auger, C. (2011) Vascular protection by natural product-derived polyphenols : In vitro and in vivo evidence. Planta Med. 77, 1161-1167.
- Nasiripourdori, A., Taly, V., Grutter, T., and Taly, A. (2011) From toxins targeting ligand gated ion channels to therapeutic molecules. Toxins 3, 260-293.
- Jiang, R., Miyamoto, A., Martz, A., Specht, A., Ishibashi, H., Kueny-Stotz, M., Chassaing, S., Brouillard, R., Prado de Carvalho, L.P., Goeldner, M., Nabekura, J., Nielsen, M., and Grutter, T. (2011) Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro. Brit. J. Pharmacol. 162, 1326-1339.
- Jiang, R., Lemoine, D., Martz, A., Taly, A., Gonin, S., Prado de Carvalho, L.P., Specht, A., and Grutter, T. (2011) Agonist trapped in ATP-binding sites of the P2X2 receptor. Proc. Natl. Acad. Sci. U. S. A. 108, 9066- 9071.
- Puliti, D., Warther, D., Orange, C., Specht, A., and Goeldner, M. (2011) Small photoactivatable molecules for controlled fluorescence activation in living cells. Bioorg. Med. Chem. 19, 1023-1029.
- Malmerberg, E., Omran, Z., Hub, J.S., Li, X., Katona, G., Westenhoff, S., Johansson, L.C., Andersson, M., Cammarata, M., Wulff, M., van der Spoel, D., Davidsson, J., Specht, A., and Neutze, R. (2011) Time-resolved WAXS reveals accelerated conformational changes in iodoretinal-substituted proteorhodopsin. Biophys. J. 101, 1345-1353.
- Nicoud, J.F., Bolze, F., Sun, X.H., Hayek, A., and Baldeck, P. (2011) Boron-containing two-photon-absorbing chromophores. 3.(1) One- and two-photon photophysical properties of p-carborane-containing fluorescent bioprobes. Inorg. Chem. 50, 4272-4278.
- Charon, S., Taly, A., Rodrigo, J., Perret, P., and Goeldner, M. (2011) Binding modes of noncompetitive GABA-channel blockers revisited using engineered affinity-labeling reactions combined with new docking studies. J. Agric. Food Chem. 59, 2803-2807.
- Wandhammer, M., Carletti, E., Van der Schans, M., Gillon, E., Nicolet, Y., Masson, P., Goeldner, M., Noort, D., and Nachon, F. (2011) Structural study of the complex stereoselectivity of human butyrylcholinesterase for the neurotoxic V-agents. J. Biol. Chem. 286, 16783-9.
- Taly, A., Colas, C., Malliavin, T., Blondel, A., Nilges, M., Corringer, P.J., and Joseph, D. (2011) Discrimination of agonists versus antagonists of nicotinic ligands based on docking onto AChBP structures. J. Mol. Graph. 30, 100-109.
- Taly, A., and Charon, S. (2011) α7 Nicotinic acetylcholine receptors : A therapeutic target in the structure era. Curr. Drug Targets 30, 100-109.