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Publications 2016

- Chiper, M., Tounsi, N., Kole, R., Kichler, A., Zuber, G. (2016) Self-aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides. Journal of Controlled Release, in press
- Ripoll, M., Neuberg, P., Kichler, A., Tounsi, N., Wagner, A., Remy, J.S. (2016) pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery. ACS Appl Mater Interfaces, in press.
- Moulay, G., Leborgne, C., Mason, A.J., Aisenbrey, C., Kichler, A., Bechinger, B. (2016) Histidine-rich designer peptides of the LAH4 family promote delivery of a multitude of cargo. Journal of Peptide Science, in press.
- Landa, M., Kotera, M., Remy, J.S., Badi, N. (2016) Preparation of poly(ethylene imine) derivatives with precisely controlled molecular weight. European Polymer Journal, in press.
- Beyrath, J. ; Chekkat, N. ; Smulski, C. R. ; Lombardo, C. M. ; Lechner, M. C. ; Seguin, C. ; Decossas, M. ; Spanedda, M. V. ; Frisch, B. ; Guichard, G. ; Fournel, S., (2016) Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels. Oncotarget, in press.
- Barallobre-Barreiro, J., Gupta, S.K., Zoccarato, A., Kitazume-Taneike, R., Fava, M., Yin, X., Werner, T., Hirt, M.N., Zampetaki, A., Viviano, A., Chong, M., Bern, M., Kourliouros, A., Domenech, N., Willeit, P., Shah, A.M., Jahangiri, M., Schaefer, L., Fischer, J.W., Iozzo, R.V., Viner, R., Thum, T., Heineke, J., Kichler, A., Otsu, K., Mayr, M. (2016) Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. Circulation. 134(11), 817-832.
- Wu, T., Heuillard, E., Linder, V., Bou About, G., Ignat, M., Dillenseger, J.P., Anton, N., Dalmier, E., Gosse, F., Foure, G., Blindauer, F., Giraudeau, C., El-Saghire, H., Bouhadjar, M., Calligaro, C., Sorg, T., Choquet, P., Vandamme, T.F., Ferrand, C., Marescaux, J., Baumert, T., Diana, M., Pessaux, P., Robinet, E. (2016) Multimodal Imaging of a Humanized Orthotopic Model of Hepatocellular Carcinoma in Immunodeficient Mice. Sci. Rep. 6, No. 35230.
- Bouchaala, R., Mercier, L., Andreiuk, B., Mély, Y., Vandamme, T.F., Anton, N., Goetz, J.G., Kymchenko, A.S. (2016) Integrity of lipid nanocarriers in bloodstream and tumor quantified by near-infrared ratiometric FRET imaging in living mice. J. Control. Release 236, 57-67.
- Akasov, R., Zaytseva-Zotova, R., Burov, S., Leko, M., Dontenwill, M., Chiper, M., Vandamme, T.F., Markvicheva, E. (2016) Formation of multicellular tumor spheroids induced by cyclic RGD-peptides and use for anticancer drug testing in vitro. Int. J. Pharm. 506, 148-57.
- Ding, S., Anton, N., Vandamme, T.F., Serra, C.A. (2016) Microfluidic nanoprecipitation systems for preparing pure drug or polymeric drug loaded nanoparticles : an overview. Exp. Op. Drug Deliv. 10, 1447-60.
- Attia, M.F., Anton, N., Khan, I.U., Serra, C.A., Messaddeq, N., Jakhmola, A., Vecchione, R., Vandamme, T.F. (2016) One-step synthesis of iron oxide polypyrrole nanoparticles encapsulating ketoprofen as model of hydrophobic drug. Int. J. Pharm. 508, 61-70.
- Attia, M.F., Anton, N., Akasov, R., Chiper, M., Markvicheva, E., Vandamme, T.F. (2016) Biodistribution and toxicity of X-ray iodinated contrast agent in nano-emulsions in function of their size. Pharm. Res. 33, 603-14.
- Akasov, R., Zaytseva-Zotova, D., Burov, S., Leko, M., Dontenwill, M., Chiper, M., Vandamme, T.F., Markvicheva, E. (2016) Formation of multicellular tumor spheroids induced by cyclic RGD-peptides and use for anticancer drug testing in vitro. Int. J. Pharm. 506, 148-57.
- Barthelemy, A. ; Ivanov, S. ; Hassane, M. ; Fontaine, J. ; Heurtault, B. ; Frisch, B. ; Faveeuw, C. ; Paget, C. ; Trottein, F., (2016) Exogenous Activation of Invariant Natural Killer T Cells by alpha-Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza. MBio , 7 (6).
- Bouche, M. ; Dahm, G. ; Wantz, M. ; Fournel, S. ; Achard, T. ; Bellemin-Laponnaz, S., (2016) Platinum(iv) N-heterocyclic carbene complexes : their synthesis, characterisation and cytotoxic activity. Dalton Trans, 45 (28), 11362-11368.
- Casset, A. ; Khayath, N. ; de Blay, F., (2016) How In Vitro Assays Contribute to Allergy Diagnosis. Curr Allergy Asthma Rep, 16 (11), 82.
- Chekkat, N. ; Dahm, G. ; Chardon, E. ; Wantz, M. ; Sitz, J. ; Decossas, M. ; Lambert, O. ; Frisch, B. ; Rubbiani, R. ; Gasser, G. ; Guichard, G. ; Fournel, S. ; Bellemin-Laponnaz, S., (2016) N-Heterocyclic Carbene-Polyethylenimine Platinum Complexes with Potent in Vitro and in Vivo Antitumor Efficacy. Bioconjug Chem, 27 (8), 1942-8.
- Diab, R. ; Virriat, A. S. ; Ronzani, C. ; Fontanay, S. ; Grandemange, S. ; Elaissari, A. ; Foliguet, B. ; Maincent, P. ; Leroy, P. ; Duvaj, R. E. ; Rihn, B. H. ; Joubert, O., (2016) Elaboration of Sterically Stabilized Liposomes for S-Nitrosoglutathione Targeting to Macrophages. J Biomed Nanotechnol, 12 (1), 217-30.
- Fend, L. ; Remy-Ziller, C. ; Foloppe, J. ; Kempf, J. ; Cochin, S. ; Barraud, L. ; Accart, N. ; Erbs, P. ; Fournel, S. ; Preville, X., (2016) Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment. Oncoimmunology, 5 (2), e1080414.
- Kakhi, Z. ; Frisch, B. ; Heurtault, B. ; Pons, F., (2016) Liposomal constructs for antitumoral vaccination by the nasal route. Biochimie, 130, 14-22.
- Pierrat, P., Kereselidze, D., Lux, M., Lebeau, L., Pons, F. (2016) Enhanced gene delivery to the lung using biodegradable polyunsaturated cationic phosphatidylcholine-detergent conjugates. Int. J. Pharm. 511, 205-218.
- Pierrat, P., Casset, A., Didier, P., Kereselidze, D., Lux, M., Pons, F., Lebeau, L. (2016) Cationic DOPC-Detergent Conjugates for Safe and Efficient in Vitro and in Vivo Nucleic Acid Delivery. Chembiochem. 17, 1771-83.
- Nothisen, M., Bagilet, J., Behr, J.P., Remy, J.S., Kotera, M. (2016) Structure Tuning of Cationic Oligospermine-siRNA Conjugates for Carrier-Free Gene Silencing. Mol. Pharm. 13, 2718-28.
- Muñoz, A., Sigwalt, D., Illescas, B. M., Luczkowiak, J., Rodriguez, L., Nierengarten, I., Holler, M., Remy, J.S., Buffet, K., Vincent, S. P., Rojo, J., Delgado, R., Nierengarten, J. F., and Martin, N. (2016) Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection. Nature Chem. 8, 50-57.
- Pierrat, P., Casset, A., Kereselidze, D., Lux, M., Pons, F., and Lebeau, L. (2016) DOPC-detergent conjugates : Fusogenic carriers for improved in vitro and in vivo gene delivery. Macromol. Biosci., 16(7), 984-989.
- El Shafey, N., Guesnon, M., Simon, F., Deprez, E., Cosette, J., Stockholm, D., Scherman, D., Bigey, P., and Kichler, A. (2016) Inhibition of the myostatin/Smad signaling pathway by short decorin-derived peptides. Exp. cell Res. 341, 187-95.
- Zuber, G. (2016) Amélioration du transfert cytosolique de protéines grâce à leur organisation dans un système de délivrance. Med. Sci. 32, 345-347.
- Majdoul, S., Seye, A.K., Kichler, A., Holic, N., Galy, A., Bechinger, B., and Fenard, D. (2016) Molecular determinants of vectofusin-1 and its derivatives for the enhancement of lentivirally mediated gene transfer into hematopoietic stem/progenitor cells. J. Biol. Chem. 291, 2161-2169.
- Simon-Yarza, M.T., Baati, T., Paci, A., Lesueur, L.L., Seck, A., Chiper, M., Gref, R., Serre, C., Couvreur, P., and Horcajada, P. (2016) Antineoplastic busulfan encapsulated in a metal organic framework nanocarrier : First in vivo results. J. Mater. Chem. B 4, 585-8.
- Attia, M.F., Anton, N., Akasov, R., Chiper, M., Markvicheva, E., and Vandamme, T.F. (2016) Biodistribution and toxicity of x-ray iodinated contrast agent in nano-emulsions in function of their size. Pharm. Res. 33, 603-14.
- Jacques, S., Leriche, G., Mosser, M., Nothisen, M., Muller, C., Remy, J.S., and Wagner, A. (2016) From solution to in-cell study of the chemical reactivity of acid sensitive functional groups : a rational approach towards improved cleavable linkers for biospecific endosomal release. Org. Biomol. Chem. 14, 4794-4803.
- Atto Al-Shuaeeb R., Kolodych, S., Koniev, O., Delacroix, S., Erb, S., Nicolay, S., Cintrat, J.C., Brion, J.D., Cianferani, S., Alami, M., Wagner, A., and Messaoudi S. (2016) Palladium-catalyzed chemoselective and biocompatible functionalization of cysteine-containing molecules at room temperature, Chem. Eur. J., 22(32), 11365-11370.
- Fend, L., Remy-Ziller, C., Foloppe, J., Kempf, J., Cochin, S., Barraud, L., Accart, N., Erbs, P., Fournel, S., and Preville, X. (2016) Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment. OncoImmunology 5, e1080414 1-11.
- Habermacher, C., Martz, A., Calimet, N., Lemoine, D., Peverini, L., Specht, A., Cecchini, M., and Grutter, T. (2016) Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel. eLife 5, e11050.
- Schmitt, J., Heitz, V., Sour, A., Bolze, F., Kessler, P., Flamigni, L., Ventura, B., Bonnet, C.S., and Toth, E. (2016) A theranostic agent combining a two-photon-absorbing photosensitizer for photodynamic therapy and a gadolinium(III) complex for MRI detection. Chem.-Eur. J. 22, 2775-86.
- Tam, D.Y., Dai, Z. ; Chan, M.S., Liu, L. S., Cheung, M.C., Bolze, F., Tin, C., and Lo, P.K., (2016) A reversible DNA logic gate platform operated by one- and two-photon excitations. Angew. Chem. Int. Ed. Engl. 55, 164-8.
- Piant, S., Specht, A., Zemelman, B., Losonczy, A., and Bolze, F. (2016) Two-photon sensitive photolabile protecting groups : From molecular engineering to nanostructuration. Mol. Cryst. Liquid Cryst. 627, 1-10.
- Piant, S., Bolze, F., and Specht, A., (2016) Two-photon uncaging, from neuroscience to materials. Opt. Mater. Express, 6(5), 1679−1691.
- Fichte, M. AH., Weyel, X. MM., Junek, S., Schäfer, F., Herbivo, C., Goeldner, M., Specht , A., Wachtveitl, J., Heckel, A., (2016) Three−Dimensional Control of DNA Hybridization by Orthogonal Two−Color Two−Photon Uncaging. Angew. Chem. Int. Ed. , 55(31), 8948−8952.
- Alam, M. M. ; Bolze, F. ; Daniel, C. ; Flamigni, L. ; Gourlaouen, C. ; Heitz, V. ; Jenni, S. ; Schmitt, J. ; Sour, A. ; Ventura, B., (2016) pi-Extended diketopyrrolopyrrole-porphyrin arrays : one- and two-photon photophysical investigations and theoretical studies. Phys Chem Chem Phys, 18 (31), 21954-65.
- Sour, A. ; Jenni, S. ; Orti-Suarez, A. ; Schmitt, J. ; Heitz, V. ; Bolze, F. ; Loureiro de Sousa, P. ; Po, C. ; Bonnet, C. S. ; Pallier, A. ; Toth, E. ; Ventura, B., (2016) Four Gadolinium(III) Complexes Appended to a Porphyrin : A Water-Soluble Molecular Theranostic Agent with Remarkable Relaxivity Suited for MRI Tracking of the Photosensitizer. Inorg Chem, 55 (9), 4545-54.
- Al-Shuaeeb, R. A. A. ; Kolodych, S. ; Koniev, O. ; Delacroix, S. ; Erb, S. ; Nicolaÿ, S. ; Cintrat, J.-C. ; Brion, J.-D. ; Cianférani, S. ; Alami, M. ; Wagner, A. ; Messaoudi, S., (2016) Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature. Chemistry – A European Journal, 22 (32), 11365-11370.
- Dovgan, I. ; Kolodych, S. ; Koniev, O. ; Wagner, A., (2016) 2-(Maleimidomethyl)-1,3-Dioxanes (MD) : a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation. Scientific Reports, 6, 30835.
- Liu, H. ; Audisio, D. ; Plougastel, L. ; Decuypere, E. ; Buisson, D.-A. ; Koniev, O. ; Kolodych, S. ; Wagner, A. ; Elhabiri, M. ; Krzyczmonik, A. ; Forsback, S. ; Solin, O. ; Gouverneur, V. ; Taran, F., (2016) Ultrafast Click Chemistry with Fluorosydnones. Angewandte Chemie International Edition, 55 (39), 12073-12077.
- Ursuegui, S. ; Mosser, M. ; Wagner, A., (2016) Copper-free click chemistry for microdroplet’s W/O interface engineering. RSC Advances, 6 (97), 94942-94948.