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Publications de l’équipe

2016

  • "Self-aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides."
    M Chiper, N Tounsi, R Kole, A Kichler, G Zuber. Journal of Controlled Release 2016, in press
  • "pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery."
    Ripoll M, Neuberg P, Kichler A, Tounsi N, Wagner A, Remy JS. ACS Appl Mater Interfaces 2016, in press
  • "Histidine-rich designer peptides of the LAH4 family promote delivery of a multitude of cargo."
    Moulay G, Leborgne C, Mason AJ, Aisenbrey C, Kichler A, Bechinger B. Journal of Peptide Science 2016, in press
  • "Preparation of poly(ethylene imine) derivatives with precisely controlled molecular weight."
    Landa M, Kotera M, Remy JS, Badi N. European Polymer Journal 2016, in press
  • "Enhanced gene delivery to the lung using biodegradable polyunsaturated cationic phosphatidylcholine-detergent conjugates."
    Pierrat P, Kereselidze D, Lux M, Lebeau L, Pons F. Int J Pharm. 2016, 511, 205-218.
  • "Cationic DOPC-Detergent Conjugates for Safe and Efficient in Vitro and in Vivo Nucleic Acid Delivery."
    Pierrat P, Casset A, Didier P, Kereselidze D, Lux M, Pons F, Lebeau L. Chembiochem. 2016, 17, 1771-83.
  • "Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation."
    Barallobre-Barreiro J, Gupta SK, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt MN, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, Shah AM, Jahangiri M, Schaefer L, Fischer JW, Iozzo RV, Viner R, Thum T, Heineke J, Kichler A, Otsu K, Mayr M. Circulation 2016, 134, 817-32.
  • "Structure Tuning of Cationic Oligospermine-siRNA Conjugates for Carrier-Free Gene Silencing."
    Nothisen M, Bagilet J, Behr JP, Remy JS, Kotera M. Mol Pharm. 2016, 13, 2718-28.
  • "From solution to in-cell study of the chemical reactivity of acid sensitive functional groups : a rational approach towards improved cleavable linker for biospecific endosomal release."
    Jacques SA, Leriche G, Mosser M, Nothisen M, Muller CD, Remy JS, Wagner A. Organic & Biomolecular Chemistry 2016, 1421, 4794-803.
  • "Organizing proteins within a delivery system improves cytosolic transfer."
    Zuber G. Med Sci (Paris). 2016, 32, 345-7.
  • "DOPC-Detergent Conjugates : Fusogenic Carriers for Improved In Vitro and In Vivo Gene Delivery."
    Pierrat P, Casset A, Kereselidze D, Lux M, Pons F, Lebeau L. Macromol Biosci. 2016, 16, 984-9.
  • "Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection."
    Muñoz A, Sigwalt D, Illescas BM, Luczkowiak J, Rodriguez L, Nierengarten I, Holler M, Remy JS, Buffet K, Vincent SP, Rojo J, Delgado R, Nierengarten JF, Martin N. Nature Chemistry 2016, 8, 50-57.
  • "Molecular determinants of Vectofusin-1 and its derivatives for the enhancement of lentiviral-mediated gene transfer into hematopoietic stem/progenitor cells."
    Majdoul S, Seye AK, Kichler A, Holic N, Galy A, Bechinger B, Fenard D. J Biol Chem. 2016, 291(5), 2161-9.
  • "Inhibition of the myostatin/Smad signaling pathway by short decorin-derived peptides."
    El Shafey N, Guesnon M, Simon F, Deprez E, Scherman D, Bigey P, Kichler A. Experimental Cell Research 2016, 341, 187-95.
  • "Antineoplastic busulfan encapsulated in a metal organic framework nanocarrier : first in vivo results."
    M. T. Simon-Yarza, T. Baati, A. Paci, L. L. Lesueur, A. Seck, M. Chiper, R. Gref, C. Serre, P. Couvreur, P. Horcajada J. Mater. Chem. B 2016, 4, 585-588.
  • "Biodistribution and Toxicity of X-Ray Iodinated Contrast Agent in Nano-emulsions in Function of Their Size."
    Attia MF, Anton N, Akasov R, Chiper M, Markvicheva E, Vandamme TF. Pharm Res. 2016, 33, 603-614.

2015

  • "A Cell-Penetrating Foldamer with a Bioreducible Linkage for Intracellular Delivery of DNA."
    Douat, C. ; Aisenbrey, C. ; Antunes, S. ; Decossas, M. ; Lambert, O. ; Bechinger, B. ; Kichler, A. ; Guichard, G. Angew Chem Int Ed Engl 2015, 54, 11133-11137.
  • "Protein Delivery System Containing a Nickel-Immobilized Polymer for Multimerization of Affinity-Purified His-Tagged Proteins Enhances Cytosolic Transfer."
    Postupalenko, V. ; Desplancq, D. ; Orlov, I. ; Arntz, Y. ; Spehner, D. ; Mely, Y. ; Klaholz, B. P. ; Schultz, P. ; Weiss, E. ; Zuber, G. Angew Chem Int Ed Engl 2015, 54, 10583-10586.
  • "Efficient in vitro and in vivo pulmonary delivery of nucleic acid by carbon dot-based nanocarriers."
    Pierrat, P. ; Wang, R. ; Kereselidze, D. ; Lux, M. ; Didier, P. ; Kichler, A. ; Pons, F. ; Lebeau, L. Biomaterials 2015, 51, 290-302.
  • "Characterization of Titratable Amphiphiles in Lipid Membranes by Fluorescence Spectroscopy."
    Pierrat, P. ; Lebeau, L. Langmuir 2015, 31, 12362-12371.
  • "Photopolymerized micelles of diacetylene amphiphile : physical characterization and cell delivery properties."
    Neuberg P, Perino A, Morin-Picardat E, Anton N, Darwich Z, Weltin D, Mely Y, Klymchenko AS, Remy JS, Wagner A. Chemical Communications 2015, 51, 11595-11598.
  • "Spiro Diorthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release."
    Leriche G, Nothisen M, Baumlin N, Muller CD, Bagnard D, Remy JS, Jacques SA, Wagner A. Bioconjugate Chemistry 2015, 26, 1461-1465.
  • "Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation."
    Flacher V, Neuberg P, Point F, Daubeuf F, Muller Q, Sigwalt D, Fauny JD, Remy JS, Frossard N, Wagner A, Mueller CG, Schaeffer E. ACS Chem Biol 2015, 10, 2697-2705.
  • "Live cell immunogold labelling of RNA polymerase II. "
    Orlov, I. ; Schertel, A. ; Zuber, G. ; Klaholz, B. ; Drillien, R. ; Weiss, E. ; Schultz, P. ; Spehner, D. Sci Rep 2015, 51, 8324.
  • "Synthesis of Monodisperse Sequence-Coded Polymers with Chain Lengths above DP100."
    Ouahabi, A. A. ; Kotera, M. ; Charles, L. ; Lutz, J.-F. ACS Macro Letters 2015, 4, 1077-1080.
  • "Synthesis of highly functionalized C-60 fullerene derivatives and their applications in material and life sciences."
    Yan, W. ; Seifermann, S. M. ; Pierrat, P. ; Braese, S. Organic & Biomolecular Chemistry 2015, 13, 25-54.

2014

  • “NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer”
    Mahindhoratep, S. ; Bouda, H.A. ; El Shafey, N. ; Scherman, D. ; Kichler, A. ; Pichon, C. ; Midoux, P. ; Mignet, N. ; Bureau, M.F. Biochim Biophys Acta. 2014, 1840, 3257-3263.
  • “Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe : application to living-cell biothiol imaging”
    Egloff, C. ; Jacques, S.A. ; Nothisen, M. ; Weltin, D. ; Calligaro, C. ; Mosser, M. ; Remy, J-S. ; Wagner, A. Chem Comm. 2014, 50, 100049-100051.
  • “Copper-chelating azides for efficient click conjugation reactions in complex media”
    Bevilacqua, V. ; King, M. ; Chaumontet, M. ; Nothisen, M. ; Gabillet, S. ; Buisson, D. ; Puente, C. ; Wagner, A. ; Taran, F. Angew Chem Int Ed Engl. 2014, 53, 5872-5876.
  • “Contrast agents for preclinical targeted X-ray imaging”
    Li, X. ; Anton, N. ; Zuber, G. ; Vandamme, T. Adv. Drug Deliv. Rev. 2014, 76, 116-133.
  • “Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles”
    Koniev, O. ; Leriche, G. ; Nothisen, M. ; Remy, J.-S. ; Strub, J.-M. ; Schaeffer-Reiss, C. ; Van Dorsselaer, A. ; Baati, R. ; Wagner, A. Bioconjugate Chem. 2014, 25, 202-206.
  • “Quantitative measurement of delivery and gene silencing activities of siRNA polyplexes containing pyridylthiourea-grafted polyethylenimines”
    Pinel, S. ; Aman, E. ; Erblang, F. ; Dietrich, J. ; Frisch, B. ; Sirman, J. ; Kichler, A. ; Sibler, A.-P. ; Dontenwill, M. ; Schaffner, F. ; Zuber, G. J. Controlled Release 2014, 182, 1-12.
  • “Intracellular delivery of functionally active proteins using self-assembling pyridylthiourea-polyethylenimine”
    Postupalenko, V. ; Sibler, A.-P. ; Desplancq, D. ; Nomine, Y. ; Spehner, D. ; Schultz, P. ; Weiss, E. ; Zuber, G. J. Controlled Release 2014, 178, 86-94.
  • Ericson, M. ; Rice, K. ; Zuber, G. “Design of Macromolecular conjugates for nucleic acid delivery.” Imperial College Press. In : Advanced Textbook on Gene Transfer, Gene Therapy and Genetic Pharmacology, editor : D. Scherman, 2014.
  • Neuberg, P. ; Kichler, A. “Recent developments in nucleic acid delivery with polyethylenimines.” Academic Press. In : L. Huang (Ed.), Non-Viral Vectors for Gene Therapy : Lipid- and Polymer-based Gene Transfer., 2014, 263–288.

2013

  • “A study of insoluble monolayers by deposition at a bubble interface”
    Anton, N. ; Pierrat, P. ; Lebeau, L. ; Vandamme, T.F. ; Bouriat, P. Soft Matter 2013, 9, 10081-10091.
  • “Oligobenzylethylenimine enriches linear polyethylenimine with a pH-sensitive membrane-disruptive property and leads to enhanced gene delivery activity”
    Chandrashekhar, C. ; Pons, B. ; Muller, C.D. ; Tounsi, N. ; Mulherkar, R. ; Zuber, G. Acta Biomaterialia 2013, 9, 4985-4993.
  • “Infectivity enhancement of different HIV-1-based lentiviral pseudotypes in presence of the cationic amphipathic peptide LAH4-L1”
    Fenard, D. ; Genries, S. ; Scherman, D. ; Galy, A. ; Martin, S. ; Kichler, A. Journal of Virological Methods 2013, 189, 375-378.
  • “Vectofusin-1, a new viral entry enhancer, strongly promotes lentiviral transduction of human hematopoietic stem cells”
    Fenard, D. ; Ingrao, D. ; Seye, A. ; Buisset, J. ; Genries, S. ; Martin, S. ; Kichler, A. ; Galy, A. Mol. Ther.—Nucleic Acids 2013, 2, E90/1-E90/10.
  • “Synthesis of optically pure [60]fullerene e,e,e-tris adducts”
    Guerra, S. ; Schillinger, F. ; Sigwalt, D. ; Holler, M. ; Nierengarten, J.-F. Chem. Commun. (Cambridge, U. K.) 2013, 49, 4752-4754.
  • “The di-t-butylsilylene protecting group as a bridging unit in linear and macrocyclic bis-malonates for the regioselective multifunctionalization of C60”
    Guerra, S. ; Trinh, T.M.N. ; Schillinger, F. ; Muhlberger, L. ; Sigwalt, D. ; Holler, M. ; Nierengarten, J.-F. Tetrahedron Lett. 2013, 54, 6251-6257.
  • “Iodinated alpha-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging”
    Li, X. ; Anton, N. ; Zuber, G. ; Zhao, M.J. ; Messaddeq, N. ; Hallouard, F. ; Fessi, H. ; Vandamme, T.F. Biomaterials 2013, 34, 481-491.
  • “Polycationic Pillar[5|arene Derivatives : Interaction with DNA and Biological Applications”
    Nierengarten, I. ; Nothisen, M. ; Sigwalt, D. ; Biellmann, T. ; Holler, M. ; Remy, J.-S. ; Nierengarten, J.-F. Chem. - Eur. J. 2013, 19, 17552-17558.
  • “Cell-penetrating cationic siRNA and lipophilic derivatives efficient at nanomolar concentrations in the presence of serum and albumin”
    Perche, P. ; Nothisen, M. ; Bagilet, J. ; Behr, J.P. ; Kotera, M. ; Remy, J.S. Journal of Controlled Release 2013, 170, 92-98.
  • “MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes”
    Philippe, L. ; Alsaleh, G. ; Pichot, A. ; Ostermann, E. ; Zuber, G. ; Frisch, B. ; Sibilia, J. ; Pfeffer, S. ; Bahram, S. ; Wachsmann, D. ; Georgel, P. Annals of the Rheumatic Diseases 2013, 72, 1071-1079.
  • “Bioresponsive Deciduous-Charge Amphiphiles for Liposomal Delivery of DNA and siRNA”
    Pierrat, P. ; Kereselidze, D. ; Wehrung, P. ; Zuber, G. ; Pons, F. ; Lebeau, L. Pharmaceutical Research 2013, 30, 1362-1379.
  • “Phospholipid-Detergent Conjugates as Novel Tools for siRNA Delivery”
    Pierrat, P. ; Laverny, G. ; Creusat, G. ; Wehrung, P. ; Strub, J.M. ; VanDorsselaer, A. ; Pons, F. ; Zuber, G. ; Lebeau, L. Chemistry-a European Journal 2013, 19, 2344-2355.
  • “Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV 1 trans-Infection”
    Schaeffer, E. ; Dehuyser, L. ; Sigwalt, D. ; Flacher, V. ; Bernacchi, S. ; Chaloin, O. ; Remy, J.-S. ; Mueller, C.G. ; Baati, R. ; Wagner, A. Bioconjugate Chem. 2013, 24, 1813-1823.
  • “An expeditious regioselective synthesis of [60]fullerene e,e,e tris-adduct building blocks”
    Sigwalt, D. ; Schillinger, F. ; Guerra, S. ; Holler, M. ; Berville, M. ; Nierengarten, J.-F. Tetrahedron Lett. 2013, 54, 4241-4244.
  • “Monolayer two-dimensional crystallization of membrane proteins”
    Lebeau, L. ; Vénien-Bryan, C. In “Methods in Molecular Biology – Electron Crystallography of Soluble and Membrane Proteins”. Schmidt-Krey, I. ; Cheng, Y. Eds, Humana Press 2013, 955, 59-72.

2012

  • “Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo”
    Creusat, G. ; Thomann, J.S. ; Maglott, A. ; Pons, B. ; Dontenwill, M. ; Guerin, E. ; Frisch, B. ; Zuber, G. Journal of Controlled Release 2012, 157, 418-426.
  • “Identification of decorin derived peptides with a zinc dependent anti-myostatin activity”
    Guiraud, S. ; van Wittenberghe, L. ; Georger, C. ; Scherman, D. ; Kichler, A. Neuromuscular Disorders 2012, 22, 1057-1068.
  • “Control of pH responsive peptide self-association during endocytosis is required for effective gene transfer”
    Iacobucci, V. ; Di Giuseppe, F. ; Bui, T.T. ; Vermeer, L.S. ; Patel, J. ; Scherman, D. ; Kichler, A. ; Drake, A.F. ; Mason, A.J. Biochimica Et Biophysica Acta-Biomembranes 2012, 1818, 1332-1341.
  • “A Cationic Phospholipid-Detergent Conjugate as a New Efficient Carrier for siRNA Delivery”
    Pierrat, P. ; Creusat, G. ; Laverny, G. ; Pons, F. ; Zuber, G. ; Lebeau, L. Chemistry-a European Journal 2012, 18, 3835-3839.
  • “Lung deposition and toxicological responses evoked by multi-walled carbon nanotubes dispersed in a synthetic lung surfactant in the mouse”
    Ronzani, C. ; Spiegelhalter, C. ; Vonesch, J.L. ; Lebeau, L. ; Pons, F. Archives of Toxicology 2012, 86, 137-149.
  • “Improvement of hyaluronic acid enzymatic stability by the grafting of amino-acids”
    Schante, C.E. ; Zuber, G. ; Herlin, C. ; Vandamme, T.F. Carbohydrate Polymers 2012, 87, 2211-2216.
  • “Smart DNA Vectors Based on Cyclodextrin Polymers : Compaction and Endosomal Release”
    Wintgens, V. ; Leborgne, C. ; Baconnais, S. ; Burckbuchler, V. ; Le Cam, E. ; Scherman, D. ; Kichler, A. ; Amiel, C. Pharmaceutical Research 2012, 29, 384-396.

2011

  • “A new family of peptide-nucleic acid nanostructures with potent transfection activities”
    Bechinger, B. ; Vidovic, V. ; Bertani, P. ; Kichler, A. Journal of Peptide Science 2011, 17, 88-93.
  • “Spleen-Resident CD4(+) and CD4(-) CD8 alpha(-) Dendritic Cell Subsets Differ in Their Ability to Prime Invariant Natural Killer T Lymphocytes”
    Bialecki, E. ; Fernandez, E.M. ; Ivanov, S. ; Paget, C. ; Fontaine, J. ; Rodriguez, F. ; Lebeau, L. ; Ehret, C. ; Frisch, B. ; Trottein, F. ; Faveeuw, C. Plos One 2011, 6.
  • “Synthesis of Poly(propylene glycol)-block-Polyethylenimine Triblock Copolymers for the Delivery of Nucleic Acids”
    Brissault, B. ; Leborgne, C. ; Scherman, D. ; Guis, C. ; Kichler, A. Macromolecular Bioscience 2011, 11, 652-661.
  • “Polyethylenimine-carbon nanotube nanohybrids for siRNA-mediated gene silencing at cellular level”
    Foillard, S. ; Zuber, G. ; Doris, E. Nanoscale 2011, 3, 1461-1464.
  • “The Reverse Block Copolymer Pluronic 25R2 Promotes DNA Transfection of Skeletal Muscle”
    Guiraud, S. ; Alimi-Guez, D. ; van Wittenberghe, L. ; Scherman, D. ; Kichler, A. Macromolecular Bioscience 2011, 11, 590-594.
  • “Radiopaque iodinated nano-emulsions for preclinical X-ray imaging”
    Hallouard, F. ; Anton, N. ; Zuber, G. ; Choquet, P. ; Li, X. ; Arntz, Y. ; Aubertin, G. ; Constantinesco, A. ; Vandamme, T.F. Rsc Advances 2011, 1, 792-801.
  • “MMT, Npeoc-protected spermine, a valuable synthon for the solid phase synthesis of oligonucleotide oligospermine conjugates via guanidine linkers”
    Perche, P. ; Kotera, M. ; Remy, J.S. Bioorganic & Medicinal Chemistry 2011, 19, 1972-1977.
  • “Synthesis of N-alanyl-hyaluronamide with high degree of substitution for enhanced resistance to hyaluronidase-mediated digestion”
    Schante, C. ; Zuber, G. ; Herlin, C. ; Vandamme, T.F. Carbohydrate Polymers 2011, 86, 747-752.
  • “Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications”
    Schante, C.E. ; Zuber, G. ; Herlin, C. ; Vandamme, T.F. Carbohydrate Polymers 2011, 85, 469-489.
  • “Pre-treatment of cells with pluronic L64 increases DNA transfection mediated by electrotransfer”
    Wasungu, L. ; Marty, A.L. ; Bureau, M.F. ; Kichler, A. ; Bessodes, M. ; Teissie, J. ; Scherman, D. ; Rols, M.P. ; Mignet, N. Journal of Controlled Release 2011, 149, 117-125.
  • “Formulation and Delivery of Splice-Correction Antisense Oligonucleotides by Amino Acid Modified Polyethylenimine (vol 7, pg 652, 2010)”
    Zaghloul, E.M. ; Viola, J.R. ; Zuber, G. ; Smith, C.I.E. ; Lundin, K.E. Molecular Pharmaceutics 2011, 8, 990-990.

2010

  • “DNAJB2 Expression in Normal and Diseased Human and Mouse Skeletal Muscle”
    Claeys, K.G. ; Sozanska, M. ; Martin, J.J. ; Lacene, E. ; Vignaud, L. ; Stockholm, D. ; Laforet, P. ; Eymard, B. ; Kichler, A. ; Scherman, D. ; Voit, T. ; Israeli, D. American Journal of Pathology 2010, 176, 2901-2910.
  • “Proton Sponge Trick for pH-Sensitive Disassembly of Polyethylenimine-Based siRNA Delivery Systems”
    Creusat, G. ; Rinaldi, A.S. ; Weiss, E. ; Elbaghdadi, R. ; Remy, J.S. ; Mulherkar, R. ; Zuber, G. Bioconjugate Chemistry 2010, 21, 994-1002.
  • “Preparation and Optical Properties of Novel 3-Alkoxycarbonyl Aza- and Diazacoumarins”
    Feau, C. ; Klein, E. ; Kerth, P. ; Lebeau, L. Synthetic Communications 2010, 40, 3033-3045.
  • “Evaluation of Positive Regulators of the Muscle Mass in Dystrophic Mouse Models”
    Guiraud, S. ; Van Wittenberghe, L. ; Georger, C. ; Scherman, D. ; Kichler, A. Human Gene Therapy 2010, 21, 778-778.
  • “Well-defined star shaped polymer-fullerene hybrids via click chemistry”
    Inglis, A.J. ; Pierrat, P. ; Muller, T. ; Brase, S. ; Barner-Kowollik, C. Soft Matter 2010, 6, 82-84.
  • “Histidine-rich amphipathic peptides promote efficient delivery of nucleic acids into mammalian cells”
    Kichler, A. ; Mason, A.J. ; Leborgne, C. ; Bechinger, B. ; Scherman, D. Human Gene Therapy 2010, 21, 1433-1433.
  • “"HFP" Fluorinated Cationic Lipids for Enhanced Lipoplex Stability and Gene Delivery”
    Klein, E. ; Ciobanu, M. ; Klein, J. ; Machi, V. ; Leborgne, C. ; Vandamme, T. ; Frisch, B. ; Pons, F. ; Kichler, A. ; Zuber, G. ; Lebeau, L. Bioconjugate Chemistry 2010, 21, 360-371.
  • “Nucleic acid transfer with hemifluorinated polycationic lipids”
    Klein, E. ; Leborgne, C. ; Ciobanu, M. ; Klein, J. ; Frisch, B. ; Pons, F. ; Zuber, G. ; Scherman, D. ; Kichler, A. ; Lebeau, L. Biomaterials 2010, 31, 4781-4788.
  • “Incorporation of 2,3-Diaminopropionic Acid into Linear Cationic Amphipathic Peptides Produces pH-Sensitive Vectors”
    Lan, Y. ; Langlet-Bertin, B. ; Abbate, V. ; Vermeer, L.S. ; Kong, X.L. ; Sullivan, K.E. ; Leborgne, C. ; Scherman, D. ; Hider, R.C. ; Drake, A.F. ; Bansal, S.S. ; Kichler, A. ; Mason, A.J. Chembiochem 2010, 11, 1266-1272.
  • “Design and Evaluation of Histidine-Rich Amphipathic Peptides for siRNA Delivery”
    Langlet-Bertin, B. ; Leborgne, C. ; Scherman, D. ; Bechinger, B. ; Mason, A.J. ; Kichler, A. Pharmaceutical Research 2010, 27, 1426-1436.
  • “Investigation of DNA Condensing Properties of Amphiphilic Triblock Cationic Polymers by Atomic Force Microscopy”
    Lidgi-Guigui, N. ; Guis, C. ; Brissault, B. ; Kichler, A. ; Leborgne, C. ; Scherman, D. ; Labdi, S. ; Curmi, P.A. Langmuir 2010, 26, 17552-17557.
  • “Polymers for Improving the In Vivo Transduction Efficiency of AAV2 Vectors”
    Moulay, G. ; Boutin, S. ; Masurier, C. ; Scherman, D. ; Kichler, A. Plos One 2010, 5.
  • “Soluble TNF-alpha receptor secretion from healthy or dystrophic mice after AAV6-mediated muscle gene transfer”
    Moulay, G. ; Masurier, C. ; Bigey, P. ; Scherman, D. ; Kichler, A. Gene Therapy 2010, 17, 1400-1410.
  • “Fasting Increases the In Vivo Gene Delivery of AAV Vectors”
    Moulay, G. ; Scherman, D. ; Kichler, A. Cts-Clinical and Translational Science 2010, 3, 333-336.
  • “Formulation and Delivery of Splice-Correction Antisense Oligonucleotides by Amino Acid Modified Polyethylenimine”
    Zaghloul, E.M. ; Viola, J.R. ; Zuber, G. ; Smith, C.I.E. ; Lundin, K.E. Molecular Pharmaceutics 2010, 7, 652-663.

2009

  • “Evaluation of the muscle gene transfer activity of a series of amphiphilic triblock copolymers”
    Alimi-Guez, D. ; Leborgne, C. ; Pembouong, G. ; Van Wittenberghe, L. ; Mignet, N. ; Scherman, D. ; Kichler, A. Journal of Gene Medicine 2009, 11, 1114-1124.
  • “Chemical synthesis, DNA incorporation and biological study of a new photocleavable 2 ’-deoxyadenosine mimic”
    Berthet, N. ; Crey-Desbiolles, C. ; Kotera, M. ; Dumy, P. Nucleic Acids Research 2009, 37, 5237-5245.
  • “Synthesis and characterization of coumarin-based europium complexes and luminescence measurements in aqueous media”
    Feau, C. ; Klein, E. ; Dosche, C. ; Kerth, P. ; Lebeau, L. Organic & Biomolecular Chemistry 2009, 7, 5259-5270.
  • “Synthesis and properties of europium complexes derived fromcoumarin-derivatized azamacrocycles”
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